HUMAN INSULIN ANALOGUES OF PROLONGED THERAPEUTICAL ACTIVITY, STABLE IN ACIDIC MEDIUM

The invention relates to human insulin derivatives possessing prolonged therapeutical activity and stability in acidic medium, and also to pharmaceutically acceptable salts thereof. The claimed human insulin derivatives can be used to manufacture a medicine for treatment or prevention of diabetes me...

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Hauptverfasser: BOGIEL MONIKA, SLAWINSKI WOJCIECH, PLUCIENNICZAK GRAZYNA, MIKOLAJCZYK JERZY, PLUCIENNICZAK ANDRZEJ, PAWLUKOWIEC TOMASZ, STEPNIEWSKI JACEK, BERNAT JUSTYNA, ADAMCZEWSKA-CECUDA VIOLETTA, SOKOLOWSKA IWONA, BOROWICZ PIOTR, KURZYNOGA DARIUSZ, GLABSKI TADEUSZ, WOJTOWICZ-KRAWIEC ANNA, KESIK -BRODACKA MALGORZATA, ZIELINSKI MARCIN, STADNIK DOROTA, ANTOSIK JAROSLAW, PSTRZOCH JACEK, MIKIEWICZ-SYGULA DIANA
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creator BOGIEL MONIKA
SLAWINSKI WOJCIECH
PLUCIENNICZAK GRAZYNA
MIKOLAJCZYK JERZY
PLUCIENNICZAK ANDRZEJ
PAWLUKOWIEC TOMASZ
STEPNIEWSKI JACEK
BERNAT JUSTYNA
ADAMCZEWSKA-CECUDA VIOLETTA
SOKOLOWSKA IWONA
BOROWICZ PIOTR
KURZYNOGA DARIUSZ
GLABSKI TADEUSZ
WOJTOWICZ-KRAWIEC ANNA
KESIK -BRODACKA MALGORZATA
ZIELINSKI MARCIN
STADNIK DOROTA
ANTOSIK JAROSLAW
PSTRZOCH JACEK
MIKIEWICZ-SYGULA DIANA
description The invention relates to human insulin derivatives possessing prolonged therapeutical activity and stability in acidic medium, and also to pharmaceutically acceptable salts thereof. The claimed human insulin derivatives can be used to manufacture a medicine for treatment or prevention of diabetes mellitus, and also they can be used for treatment of patients suffering from diabetes mellitus. Изобретение относится к производным инсулина человека, обладающим пролонгированной терапевтической активностью и стабильностью в кислой среде, а также к их фармацевтически приемлемым солям. Заявленные производные инсулина человека могут быть использованы для производства лекарственного препарата для лечения или профилактики сахарного диабета, а также могут быть использованы при лечении пациентов, страдающих сахарным диабетом.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title HUMAN INSULIN ANALOGUES OF PROLONGED THERAPEUTICAL ACTIVITY, STABLE IN ACIDIC MEDIUM
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