OPHTHALMOLOGICAL GEL AND A METHOD FOR THE USE THEREOF

The invention relates to medicine, in particular, to ophthalmology and can be used as an artificial lacrimal fluid for the treatment of "dry eye" syndrome, traumatic injuries, trophic disorders and chemical burn of cohjunctiva, cornea and diseases associated with cornea operations. The inventive ophthalmological gel comprises 0.2-1.0% low-cross-linked polyacrylic acid and/or derivatives thereof, comprising a carbixylic group, preservatives, stabilizers, a medicinal substance selected from a reparant group 1-( -oxyethyl)-4,6-dimethyl-1,2-dihydro-2-oxypyrimidine (xymedon), clean water and has a pH value within the range pH of lachrymal liquid. According to the invention said gel variant further comprises an aqueous solution of polyethyleneoxcides, NaOH in the amount sufficient to prepare gel with pH 6.0-7.9, containing as preservatives and stabilisers benzalkonium choride, edetate disodium and aminoglycoside antibiotic - gentamicin sulfate with the following component ratio, wt.%: low-cross-linked polyacrylic acid and/or derivatives thereof, comprising a carboxylic group 0.2-1.0; 10-30% aqueous solution of polyethyleneoxide - 2-10; xymedon - 1-10; benzalkonium chloride - 0.005-0.015; edetate disodium (trilon B) - 0.002-0.004; gentamicin sulfate - 0.02-0.03; clean water - up to 100. The inventive gel production method consists in adding an aqueous 10-30% polyethylenoxide solution into a dry powder of low-cross-linked polyacrylic acid associated with rapid agitation, polyethylenoxide being taken at least in a tenfold excess with respect to the mass of the powder, in adding, while agitating, clean water in a quantity equal to 70-90% the total mass of the gel, in adjusting a pH value to a value of 6.0-7.0 by means of a sodium hydroxide solution, in adding, while agitating, an alkali stabilizer, preservative and antibiotic solution, which is previously prepared in a separate reactor, by mixing the aqueous solutions of benzalkonium chloride, bisodium edetate and gentamicin sulphate, in subsequently adding a 10-20% sodium hydroxide solution, in adding xymedon at a mass concentration of 1-10%, in adjusting, for the second time, the pH value to a required value 10-20% by means of a sodium hydroxide solution and in sterilizing the thus produced gel. Изобретение относится к медицине, в частности к офтальмологии, и может быть использовано в качестве искусственной слезной жидкости для лечения синдрома "сухого глаза", травматических повреждений, трофических нарушений и хи