HYDROXYSYRER

The invention concerns novel racemic and optically active mono- and di-hydroxy alkanoic acids bearing phenyl and/or alkyl substituents, processes for their preparation, and pharmaceutical compositions for therapeutic use in the treatment of duodenal or gastric ulcers. Representative compounds of the...

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Hauptverfasser: STRAWSON C J, CRAWLEY G C, ALDRIDGE D C
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creator STRAWSON C J
CRAWLEY G C
ALDRIDGE D C
description The invention concerns novel racemic and optically active mono- and di-hydroxy alkanoic acids bearing phenyl and/or alkyl substituents, processes for their preparation, and pharmaceutical compositions for therapeutic use in the treatment of duodenal or gastric ulcers. Representative compounds of the invention are 2-(5 beta -n-butyl-4 beta -hydroxy-2-oxo-tetrahydrofuran-3 beta -yl)-2 alpha -methyl-acetic acid and 3 alpha -methyl-5 beta -(1 beta -hydroxy-n-pentyl)-2-oxo-tetrahydrofuran-4 beta -ylcarboxylic acid.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HYDROXYSYRER
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