STABILT VÆSKEFORMIGT FARMACEUTISK PRÆPARAT

The present invention provides a stable liquid pharmaceutical formulation containing: an antibody or its antigen-binding fragment; a surfactant; a sugar or its derivative; and a buffer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity while containing...

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Hauptverfasser: LEE, Joon Won, KIM, So Young, HONG, Su Hyeon, KIM, Su Jung, OH, Jun Seok, SHIN, Yeon Kyeong, HAN, Won Yong
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creator LEE, Joon Won
KIM, So Young
HONG, Su Hyeon
KIM, Su Jung
OH, Jun Seok
SHIN, Yeon Kyeong
HAN, Won Yong
description The present invention provides a stable liquid pharmaceutical formulation containing: an antibody or its antigen-binding fragment; a surfactant; a sugar or its derivative; and a buffer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity while containing a high content of the antibody, has excellent long-term storage ability based on excellent stability under accelerated conditions and severe conditions, and may be administered subcutaneously.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title STABILT VÆSKEFORMIGT FARMACEUTISK PRÆPARAT
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