RIBOSOMDISPLAYKOMPLEKS OG FREMSTILLINGSFREMGANGSMÅDE DERTIL
The objective of the present invention is to provide a ribosome complex which can be produced without a cumbersome reaction procedure and of which displayed polypeptide is modified without impairing a function of the ribosome, particularly function to produce a polypeptide library, and a method for...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | dan |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SHIKAKURA, Toshihiro MAEDA, Hirofumi KITA, Hiroshi TAKATSU, Keishi |
| description | The objective of the present invention is to provide a ribosome complex which can be produced without a cumbersome reaction procedure and of which displayed polypeptide is modified without impairing a function of the ribosome, particularly function to produce a polypeptide library, and a method for producing the ribosome complex. The method for producing a ribosome display complex according to the present invention is characterized in comprising the steps of translating the mRNA molecule in a cell-free peptide synthesis system utilizing the ribosome to obtain a ribosome complex comprising an unmodified polypeptide chain, the mRNA molecule and the ribosome, and modifying the unmodified polypeptide chain by reacting the side chain reactive functional group in the unmodified polypeptide chain with a modifying reagent. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_DK3467107TT3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>DK3467107TT3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_DK3467107TT33</originalsourceid><addsrcrecordid>eNrjZLAJ8nTyD_b3dfEMDvBxjPT29w3wcfUOVvB3V3ALcvUNDvH08fH0cw8GcdwdgQzfw60urgourkFAGR4G1rTEnOJUXijNzaDo5hri7KGbWpAfn1pckJicmpdaEu_ibWxiZm5oYB4SYmxMjBoAuJUrdw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>RIBOSOMDISPLAYKOMPLEKS OG FREMSTILLINGSFREMGANGSMÅDE DERTIL</title><source>esp@cenet</source><creator>SHIKAKURA, Toshihiro ; MAEDA, Hirofumi ; KITA, Hiroshi ; TAKATSU, Keishi</creator><creatorcontrib>SHIKAKURA, Toshihiro ; MAEDA, Hirofumi ; KITA, Hiroshi ; TAKATSU, Keishi</creatorcontrib><description>The objective of the present invention is to provide a ribosome complex which can be produced without a cumbersome reaction procedure and of which displayed polypeptide is modified without impairing a function of the ribosome, particularly function to produce a polypeptide library, and a method for producing the ribosome complex. The method for producing a ribosome display complex according to the present invention is characterized in comprising the steps of translating the mRNA molecule in a cell-free peptide synthesis system utilizing the ribosome to obtain a ribosome complex comprising an unmodified polypeptide chain, the mRNA molecule and the ribosome, and modifying the unmodified polypeptide chain by reacting the side chain reactive functional group in the unmodified polypeptide chain with a modifying reagent.</description><language>dan</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMBINATORIAL CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220627&DB=EPODOC&CC=DK&NR=3467107T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220627&DB=EPODOC&CC=DK&NR=3467107T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHIKAKURA, Toshihiro</creatorcontrib><creatorcontrib>MAEDA, Hirofumi</creatorcontrib><creatorcontrib>KITA, Hiroshi</creatorcontrib><creatorcontrib>TAKATSU, Keishi</creatorcontrib><title>RIBOSOMDISPLAYKOMPLEKS OG FREMSTILLINGSFREMGANGSMÅDE DERTIL</title><description>The objective of the present invention is to provide a ribosome complex which can be produced without a cumbersome reaction procedure and of which displayed polypeptide is modified without impairing a function of the ribosome, particularly function to produce a polypeptide library, and a method for producing the ribosome complex. The method for producing a ribosome display complex according to the present invention is characterized in comprising the steps of translating the mRNA molecule in a cell-free peptide synthesis system utilizing the ribosome to obtain a ribosome complex comprising an unmodified polypeptide chain, the mRNA molecule and the ribosome, and modifying the unmodified polypeptide chain by reacting the side chain reactive functional group in the unmodified polypeptide chain with a modifying reagent.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMBINATORIAL CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAJ8nTyD_b3dfEMDvBxjPT29w3wcfUOVvB3V3ALcvUNDvH08fH0cw8GcdwdgQzfw60urgourkFAGR4G1rTEnOJUXijNzaDo5hri7KGbWpAfn1pckJicmpdaEu_ibWxiZm5oYB4SYmxMjBoAuJUrdw</recordid><startdate>20220627</startdate><enddate>20220627</enddate><creator>SHIKAKURA, Toshihiro</creator><creator>MAEDA, Hirofumi</creator><creator>KITA, Hiroshi</creator><creator>TAKATSU, Keishi</creator><scope>EVB</scope></search><sort><creationdate>20220627</creationdate><title>RIBOSOMDISPLAYKOMPLEKS OG FREMSTILLINGSFREMGANGSMÅDE DERTIL</title><author>SHIKAKURA, Toshihiro ; MAEDA, Hirofumi ; KITA, Hiroshi ; TAKATSU, Keishi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DK3467107TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>dan</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMBINATORIAL CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SHIKAKURA, Toshihiro</creatorcontrib><creatorcontrib>MAEDA, Hirofumi</creatorcontrib><creatorcontrib>KITA, Hiroshi</creatorcontrib><creatorcontrib>TAKATSU, Keishi</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHIKAKURA, Toshihiro</au><au>MAEDA, Hirofumi</au><au>KITA, Hiroshi</au><au>TAKATSU, Keishi</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RIBOSOMDISPLAYKOMPLEKS OG FREMSTILLINGSFREMGANGSMÅDE DERTIL</title><date>2022-06-27</date><risdate>2022</risdate><abstract>The objective of the present invention is to provide a ribosome complex which can be produced without a cumbersome reaction procedure and of which displayed polypeptide is modified without impairing a function of the ribosome, particularly function to produce a polypeptide library, and a method for producing the ribosome complex. The method for producing a ribosome display complex according to the present invention is characterized in comprising the steps of translating the mRNA molecule in a cell-free peptide synthesis system utilizing the ribosome to obtain a ribosome complex comprising an unmodified polypeptide chain, the mRNA molecule and the ribosome, and modifying the unmodified polypeptide chain by reacting the side chain reactive functional group in the unmodified polypeptide chain with a modifying reagent.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | dan |
| recordid | cdi_epo_espacenet_DK3467107TT3 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | RIBOSOMDISPLAYKOMPLEKS OG FREMSTILLINGSFREMGANGSMÅDE DERTIL |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T20%3A05%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SHIKAKURA,%20Toshihiro&rft.date=2022-06-27&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EDK3467107TT3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |