HEDGEHOG-ANTAGONISTER MED ZINKBINDINGSDELE

The present invention provides compounds which antagonize hedgehog signaling and inhibit HDAC activity. The compounds can be used in methods of treating proliferative diseases and disorders such as cancer.

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Hauptverfasser: CAI, Xiong, ZHAI, Haixiao, QIAN, Changgeng
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creator CAI, Xiong
ZHAI, Haixiao
QIAN, Changgeng
description The present invention provides compounds which antagonize hedgehog signaling and inhibit HDAC activity. The compounds can be used in methods of treating proliferative diseases and disorders such as cancer.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HEDGEHOG-ANTAGONISTER MED ZINKBINDINGSDELE
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