FREMGANGSMÅDE TIL FREMSTILLING AF N-[(6-CHLORPYRIDIN-3-YL)METHYL]-2,2-DIFLUORETHAN-1-AMIN VED HJÆLP AF ALKYLERING AF 2,2-DIFLUORETHYLAMIN

FREMGANGSMÅDE TIL FREMSTILLING AF N-[(6-CHLORPYRIDIN-3-YL)METHYL]-2,2-DIFLUORETHAN-1-AMIN VED HJÆLP AF ALKYLERING AF 2,2-DIFLUORETHYLAMIN

The invention relates to a method for the preparation of N-[(6-chloropyridino-3-yl)methyl]-2,2-difluoroethane-1-amine of formula (III) wherein the 2,2-difluoroethylamine of formula (I) is reacted with a halide of formula (II) in the presence of a hydroxide of an alkali metal or alkaline earth metal.

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Hauptverfasser: SCHLEGEL, Günter, SCHNATTERER, Albert, MORADI, Wahed Ahmed
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator SCHLEGEL, Günter
SCHNATTERER, Albert
MORADI, Wahed Ahmed
description The invention relates to a method for the preparation of N-[(6-chloropyridino-3-yl)methyl]-2,2-difluoroethane-1-amine of formula (III) wherein the 2,2-difluoroethylamine of formula (I) is reacted with a halide of formula (II) in the presence of a hydroxide of an alkali metal or alkaline earth metal.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title FREMGANGSMÅDE TIL FREMSTILLING AF N-[(6-CHLORPYRIDIN-3-YL)METHYL]-2,2-DIFLUORETHAN-1-AMIN VED HJÆLP AF ALKYLERING AF 2,2-DIFLUORETHYLAMIN
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