HIDTIL UKENDTE AZAINDOLDERIVATER SOM SELEKTIVE HISTONDEACETYLASE (HDAC)-INHIBITORER OG FARMACEUTISKE SAMMENSÆTNINGER, DER OMFATTER DISSE
The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the prepara...
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| creator | LEE, Changsik OH, Jung Taek SONG, Hyeseung KIM, Ilhyang BAE, Miseon YANG, Hyun-Mo LEE, Jae Kwang HA, Nina CHOI, DaeKyu KIM, Soyoung BAE, Daekwon CHOI, Youngil MIN, JaeKi LIM, Hyojin LEE, Changkon |
| description | The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases. |
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The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.</description><language>dan</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190107&DB=EPODOC&CC=DK&NR=3080125T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190107&DB=EPODOC&CC=DK&NR=3080125T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE, Changsik</creatorcontrib><creatorcontrib>OH, Jung Taek</creatorcontrib><creatorcontrib>SONG, Hyeseung</creatorcontrib><creatorcontrib>KIM, Ilhyang</creatorcontrib><creatorcontrib>BAE, Miseon</creatorcontrib><creatorcontrib>YANG, Hyun-Mo</creatorcontrib><creatorcontrib>LEE, Jae Kwang</creatorcontrib><creatorcontrib>HA, Nina</creatorcontrib><creatorcontrib>CHOI, DaeKyu</creatorcontrib><creatorcontrib>KIM, Soyoung</creatorcontrib><creatorcontrib>BAE, Daekwon</creatorcontrib><creatorcontrib>CHOI, Youngil</creatorcontrib><creatorcontrib>MIN, JaeKi</creatorcontrib><creatorcontrib>LIM, Hyojin</creatorcontrib><creatorcontrib>LEE, Changkon</creatorcontrib><title>HIDTIL UKENDTE AZAINDOLDERIVATER SOM SELEKTIVE HISTONDEACETYLASE (HDAC)-INHIBITORER OG FARMACEUTISKE SAMMENSÆTNINGER, DER OMFATTER DISSE</title><description>The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. 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The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HIDTIL UKENDTE AZAINDOLDERIVATER SOM SELEKTIVE HISTONDEACETYLASE (HDAC)-INHIBITORER OG FARMACEUTISKE SAMMENSÆTNINGER, DER OMFATTER DISSE |
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