Sammensætninger omfattende tværbundne kationbytningspolymerer og anvendelse ved behandling af hyperkaliæmi

The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties...

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Hauptverfasser: HALFON, Sherin, MILLS, Jonathan, BURDICK, Michael, CHIDAMBARAM, Ramakrishnan, LIU, Mingjun, MANSKY, Paul, CONNOR, Eric, STRUEVER, Werner, CHANG, Han-Ting, HUANG, I-Zu, CHARMOT, Dominique, ALBRECHT, Detlef
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creator HALFON, Sherin
MILLS, Jonathan
BURDICK, Michael
CHIDAMBARAM, Ramakrishnan
LIU, Mingjun
MANSKY, Paul
CONNOR, Eric
STRUEVER, Werner
CHANG, Han-Ting
HUANG, I-Zu
CHARMOT, Dominique
ALBRECHT, Detlef
description The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Sammensætninger omfattende tværbundne kationbytningspolymerer og anvendelse ved behandling af hyperkaliæmi
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