SMB-fremgangsmåde til fremstilling af EPA af høj renhedsgrad ud af fiskeolie
The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of: (i) purifying the feed mixture in a chromatographic separati...
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| creator | Morrison, Angus Oroskar, Anil Nair Rema, Rakesh Vikraman Kelliher, Adam Agarwal, Abhilesh |
| description | The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of:
(i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and
(ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and
(iii) purifying the second intermediate product obtained in (ii) in a chromatographic separation step using a different chromatographic apparatus to that used in the second separation step, to obtain the PUFA product; wherein
an aqueous organic solvent is used as eluent in each separation step;
saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step;
the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and
the PUFA product obtained in the third separation step contains EPA or an EPA derivative in an amount greater than 90 wt%. |
| format | Patent |
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(i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and
(ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and
(iii) purifying the second intermediate product obtained in (ii) in a chromatographic separation step using a different chromatographic apparatus to that used in the second separation step, to obtain the PUFA product; wherein
an aqueous organic solvent is used as eluent in each separation step;
saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step;
the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and
the PUFA product obtained in the third separation step contains EPA or an EPA derivative in an amount greater than 90 wt%.</description><language>dan</language><subject>ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES ; CANDLES ; CHEMISTRY ; DETERGENTS ; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS,OILS, OR FATTY ACIDS OBTAINED THEREFROM ; FATTY ACIDS FROM FATS, OILS OR WAXES ; FATTY ACIDS THEREFROM ; METALLURGY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; SEPARATION ; TRANSPORTING</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180326&DB=EPODOC&CC=DK&NR=2886176T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180326&DB=EPODOC&CC=DK&NR=2886176T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Morrison, Angus</creatorcontrib><creatorcontrib>Oroskar, Anil</creatorcontrib><creatorcontrib>Nair Rema, Rakesh Vikraman</creatorcontrib><creatorcontrib>Kelliher, Adam</creatorcontrib><creatorcontrib>Agarwal, Abhilesh</creatorcontrib><title>SMB-fremgangsmåde til fremstilling af EPA af høj renhedsgrad ud af fiskeolie</title><description>The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of:
(i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and
(ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and
(iii) purifying the second intermediate product obtained in (ii) in a chromatographic separation step using a different chromatographic apparatus to that used in the second separation step, to obtain the PUFA product; wherein
an aqueous organic solvent is used as eluent in each separation step;
saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step;
the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and
the PUFA product obtained in the third separation step contains EPA or an EPA derivative in an amount greater than 90 wt%.</description><subject>ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES</subject><subject>CANDLES</subject><subject>CHEMISTRY</subject><subject>DETERGENTS</subject><subject>FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS,OILS, OR FATTY ACIDS OBTAINED THEREFROM</subject><subject>FATTY ACIDS FROM FATS, OILS OR WAXES</subject><subject>FATTY ACIDS THEREFROM</subject><subject>METALLURGY</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>SEPARATION</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAL9nXSTStKzU1PzEsvzj28NCVVoSQzRwEkVAxk5GTmpSskpim4BjiCqIzDO7IUilLzMlJTitOLElMUSlNAwmmZxdmp-TmZqTwMrGmJOcWpvFCam0HRzTXE2UM3tSA_PrW4IDE5NS-1JN7F28jCwszQ3CwkxNiYGDUASjg3RA</recordid><startdate>20180326</startdate><enddate>20180326</enddate><creator>Morrison, Angus</creator><creator>Oroskar, Anil</creator><creator>Nair Rema, Rakesh Vikraman</creator><creator>Kelliher, Adam</creator><creator>Agarwal, Abhilesh</creator><scope>EVB</scope></search><sort><creationdate>20180326</creationdate><title>SMB-fremgangsmåde til fremstilling af EPA af høj renhedsgrad ud af fiskeolie</title><author>Morrison, Angus ; Oroskar, Anil ; Nair Rema, Rakesh Vikraman ; Kelliher, Adam ; Agarwal, Abhilesh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DK2886176TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>dan</language><creationdate>2018</creationdate><topic>ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES</topic><topic>CANDLES</topic><topic>CHEMISTRY</topic><topic>DETERGENTS</topic><topic>FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS,OILS, OR FATTY ACIDS OBTAINED THEREFROM</topic><topic>FATTY ACIDS FROM FATS, OILS OR WAXES</topic><topic>FATTY ACIDS THEREFROM</topic><topic>METALLURGY</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>SEPARATION</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>Morrison, Angus</creatorcontrib><creatorcontrib>Oroskar, Anil</creatorcontrib><creatorcontrib>Nair Rema, Rakesh Vikraman</creatorcontrib><creatorcontrib>Kelliher, Adam</creatorcontrib><creatorcontrib>Agarwal, Abhilesh</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Morrison, Angus</au><au>Oroskar, Anil</au><au>Nair Rema, Rakesh Vikraman</au><au>Kelliher, Adam</au><au>Agarwal, Abhilesh</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SMB-fremgangsmåde til fremstilling af EPA af høj renhedsgrad ud af fiskeolie</title><date>2018-03-26</date><risdate>2018</risdate><abstract>The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of:
(i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and
(ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and
(iii) purifying the second intermediate product obtained in (ii) in a chromatographic separation step using a different chromatographic apparatus to that used in the second separation step, to obtain the PUFA product; wherein
an aqueous organic solvent is used as eluent in each separation step;
saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step;
the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and
the PUFA product obtained in the third separation step contains EPA or an EPA derivative in an amount greater than 90 wt%.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES CANDLES CHEMISTRY DETERGENTS FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS,OILS, OR FATTY ACIDS OBTAINED THEREFROM FATTY ACIDS FROM FATS, OILS OR WAXES FATTY ACIDS THEREFROM METALLURGY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SEPARATION TRANSPORTING |
| title | SMB-fremgangsmåde til fremstilling af EPA af høj renhedsgrad ud af fiskeolie |
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