1H-benzo [d] imidazol-5-yl-forbindelser og et sammensætning til behandling af inflammatoriske sygdomme

The heterocyclic compound according to the present invention may treat and prevent inflammatory diseases and heal skin wounds, and particularly, have effects of recovering damaged skin barrier, reducing inflammation and pruritus in inflammatory skin diseases. In addition, the composition containing...

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Hauptverfasser: PARK, BYEONG DEOG, PARK, TAE KYO, WOO, SUNG HO, JEON, JEONG EUN, GWAK, HYUNG SUB, KIM, YONG ZU, KIM, UK IL, YUN, JOUNG YUL, JEONG, SE KYOO, CHOI, HYUNG MOOK, LEE, DAE YON, LEE, HYANG SOOK
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creator PARK, BYEONG DEOG
PARK, TAE KYO
WOO, SUNG HO
JEON, JEONG EUN
GWAK, HYUNG SUB
KIM, YONG ZU
KIM, UK IL
YUN, JOUNG YUL
JEONG, SE KYOO
CHOI, HYUNG MOOK
LEE, DAE YON
LEE, HYANG SOOK
description The heterocyclic compound according to the present invention may treat and prevent inflammatory diseases and heal skin wounds, and particularly, have effects of recovering damaged skin barrier, reducing inflammation and pruritus in inflammatory skin diseases. In addition, the composition containing the compound according to the present invention as an active ingredient may be used to alleviate various inflammatory diseases and diseases in which PAR-2 is excessively expressed, and particularly, the composition may inhibit activity of PAR-2 in skin, such that the composition may be used as a composition having anti-inflammatory function in inflammatory skin diseases including atopic dermatitis, or the like.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
title 1H-benzo [d] imidazol-5-yl-forbindelser og et sammensætning til behandling af inflammatoriske sygdomme
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