L-DIHYDRO-2-OXOQUINOLINFORBINDELSER SOM 5-HT4-RECEPTORLIGANDER

The present invention relates to novel 1,2-dihydro-2-oxoquinoline compounds of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention...

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Hauptverfasser: MOHAMMED, Abdul, Rasheed, SHINDE, Anil, Karbhari, BHYRAPUNENI, Gopinadh, RAVULA, Jyothsna, AHMAD, Ishtiyaque, NIROGI, Ramakrishna, KANDIKERE, Nagaraj, Vishwottam, KAMBHAMPATI, Rama, Sastri, PATNALA, Sriramachandra, Murthy, JAYARAJAN, Pradeep, JASTI, Venkateswarlu
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creator MOHAMMED, Abdul, Rasheed
SHINDE, Anil, Karbhari
BHYRAPUNENI, Gopinadh
RAVULA, Jyothsna
AHMAD, Ishtiyaque
NIROGI, Ramakrishna
KANDIKERE, Nagaraj, Vishwottam
KAMBHAMPATI, Rama, Sastri
PATNALA, Sriramachandra, Murthy
JAYARAJAN, Pradeep
JASTI, Venkateswarlu
description The present invention relates to novel 1,2-dihydro-2-oxoquinoline compounds of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The compounds of the present invention are useful in the treatment/prevention of various disorders that are mediated by 5-HT4 receptor activity.
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The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title L-DIHYDRO-2-OXOQUINOLINFORBINDELSER SOM 5-HT4-RECEPTORLIGANDER
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