N-substituerede glycin-derivater: Hydroxylase-inhibitorer

The invention described herein relates to certain pyridazinedione N-substituted glycine derivatives which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.

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Hauptverfasser: MYERS, ANDREA, K, ZIMMERMAN, MICHAEL, N, DUFFY, KEVIN, J, MILLER, WILLIAM, HENRY, SHAW, ANTONY, N
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creator MYERS, ANDREA, K
ZIMMERMAN, MICHAEL, N
DUFFY, KEVIN, J
MILLER, WILLIAM, HENRY
SHAW, ANTONY, N
description The invention described herein relates to certain pyridazinedione N-substituted glycine derivatives which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title N-substituerede glycin-derivater: Hydroxylase-inhibitorer
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