Fast farmaceutisk sammensætning omfattende valsartan
This invention relates to a solid pharmaceutical composition containing valsartan particles characterized in that the D 50 of said valsartan particles is 150 µm or below and that the valsartan particles have a maximum diameter of no more than 1100 µm, as determined by electron microscopy, and that i...
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creator | VRBINC, MIHA RANGUS, MARIJA CERNOSA, LIDIJA BEVEC, FRANCI SLANC VOVK, JANIKA ZUPANCIC, SILVO |
description | This invention relates to a solid pharmaceutical composition containing valsartan particles characterized in that the D 50 of said valsartan particles is 150 µm or below and that the valsartan particles have a maximum diameter of no more than 1100 µm, as determined by electron microscopy, and that it comprises 30-70 wt.-% of valsartan, 10-70 wt.-% of a diluent, 1-20 wt.-% of a disintegrant, 1-20 wt.-% of a binder and 1-10% of a lubricant, wherein the disintegrant is carboxymethylcellulose sodium. |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | Fast farmaceutisk sammensætning omfattende valsartan |
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