New cyclic amine cpds
Cyclic amine cpds. of formula (I) and their salts are new. J is (a) a gp., opt. substd., of: phenyl, pyridyl, pyrazyl, cyclohexyl, quino(xa)lyl or furyl; (b) a monovalent or divalent gp., where the phenyl may have substit(s), of: indan(ol)yl, (iii) inden(on)yl, indan(edio)hyl, tetralonyl, benzosuber...
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creator | SASAKI, JUN OGURA, HIROO HIGURASHI, KUNIZOU ARAKI, SHIN TSUCHIYA, YUTAKA KOZASA, MICHIKO SUGIMOTO, HACHIRO KARIBE, NORIE IIMURA, YOICHI KOZASA, TAKASHI YAMATSU, KIYOMI YAMANISHI, YOSHIHARU KUBOTA, ATSUHIKO |
description | Cyclic amine cpds. of formula (I) and their salts are new. J is (a) a gp., opt. substd., of: phenyl, pyridyl, pyrazyl, cyclohexyl, quino(xa)lyl or furyl; (b) a monovalent or divalent gp., where the phenyl may have substit(s), of: indan(ol)yl, (iii) inden(on)yl, indan(edio)hyl, tetralonyl, benzosuberonyl, or C6H5-CO-CH(CH3)-; (c) a monovalent gp. derived from a cyclic amide cpd. (d) lower alkyl; or (e) R21-CH=CH- (R21 = H or (lower alkoxycarbonyl). B = (CHR22)r, CO(CHR22)r, NR4-(HCR22)r, CO-NR5-(CHR22)r, CH=CH-(CHR22)r, OCOO-(CHR22)r, OOC-NH-(CHR22)r, NH-CO-(CHR32)4, CH2CONH-(CHR22)r, (CH2)2CONH-(CHR22)r, CH(OH)-(CHR22)r, CH(OH)-(CHR22)r, = (CH-CH=CH)b, =CH-(CH2)c, =(CH-CH)d, COCH=CH-CH2, COCH2-CH(CH(OH)CH2, CH(CH3)CONHCH2, CH=CHCONH(CH2)2, NH, O, S, dialkylaminoalkylcarbonyl or lower alkoxycarbonyl; R4 = H, acyl, lower alkyl(sulphonyl), (substd.)phenyl, or (substd.)benzyl; R5 = H, lower alkyl or phenyl, r = 0-10; R22 = H or Me such that one alkylene may have no CH3 or one or more CH3; b = 1-3; c = 0-9; d = 0-5; T = N or C (i) Q = N, C or (i) q = 1-3; K = H, (substd.) phenyl, arylalkyl in which the phenyl may be substd. cinnamyl, lower alkyl, pyridylmethyl, cyclo(alkyl)alkyl, adamantanemethyl, furylmethyl, lower alkoxycarbonyl or acyl; and dotted lines is a single-or double-bond. 1-benzyl-4-((5,6-dimethoxy -1-indanon)- 2-ylidenyl)methyl) piperidine hydrochlorideis and example. |
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fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_DK175246BB1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>DK175246BB1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_DK175246BB13</originalsourceid><addsrcrecordid>eNrjZBD1Sy1XSK5MzslMVkjMzcxLVUguSCnmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxLt6G5qZGJmZOTobGRCgBAA6rIGU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>New cyclic amine cpds</title><source>esp@cenet</source><creator>SASAKI, JUN ; OGURA, HIROO ; HIGURASHI, KUNIZOU ; ARAKI, SHIN ; TSUCHIYA, YUTAKA ; KOZASA, MICHIKO ; SUGIMOTO, HACHIRO ; KARIBE, NORIE ; IIMURA, YOICHI ; KOZASA, TAKASHI ; YAMATSU, KIYOMI ; YAMANISHI, YOSHIHARU ; KUBOTA, ATSUHIKO</creator><creatorcontrib>SASAKI, JUN ; OGURA, HIROO ; HIGURASHI, KUNIZOU ; ARAKI, SHIN ; TSUCHIYA, YUTAKA ; KOZASA, MICHIKO ; SUGIMOTO, HACHIRO ; KARIBE, NORIE ; IIMURA, YOICHI ; KOZASA, TAKASHI ; YAMATSU, KIYOMI ; YAMANISHI, YOSHIHARU ; KUBOTA, ATSUHIKO</creatorcontrib><description>Cyclic amine cpds. of formula (I) and their salts are new. J is (a) a gp., opt. substd., of: phenyl, pyridyl, pyrazyl, cyclohexyl, quino(xa)lyl or furyl; (b) a monovalent or divalent gp., where the phenyl may have substit(s), of: indan(ol)yl, (iii) inden(on)yl, indan(edio)hyl, tetralonyl, benzosuberonyl, or C6H5-CO-CH(CH3)-; (c) a monovalent gp. derived from a cyclic amide cpd. (d) lower alkyl; or (e) R21-CH=CH- (R21 = H or (lower alkoxycarbonyl). B = (CHR22)r, CO(CHR22)r, NR4-(HCR22)r, CO-NR5-(CHR22)r, CH=CH-(CHR22)r, OCOO-(CHR22)r, OOC-NH-(CHR22)r, NH-CO-(CHR32)4, CH2CONH-(CHR22)r, (CH2)2CONH-(CHR22)r, CH(OH)-(CHR22)r, CH(OH)-(CHR22)r, = (CH-CH=CH)b, =CH-(CH2)c, =(CH-CH)d, COCH=CH-CH2, COCH2-CH(CH(OH)CH2, CH(CH3)CONHCH2, CH=CHCONH(CH2)2, NH, O, S, dialkylaminoalkylcarbonyl or lower alkoxycarbonyl; R4 = H, acyl, lower alkyl(sulphonyl), (substd.)phenyl, or (substd.)benzyl; R5 = H, lower alkyl or phenyl, r = 0-10; R22 = H or Me such that one alkylene may have no CH3 or one or more CH3; b = 1-3; c = 0-9; d = 0-5; T = N or C (i) Q = N, C or (i) q = 1-3; K = H, (substd.) phenyl, arylalkyl in which the phenyl may be substd. cinnamyl, lower alkyl, pyridylmethyl, cyclo(alkyl)alkyl, adamantanemethyl, furylmethyl, lower alkoxycarbonyl or acyl; and dotted lines is a single-or double-bond. 1-benzyl-4-((5,6-dimethoxy -1-indanon)- 2-ylidenyl)methyl) piperidine hydrochlorideis and example.</description><edition>7</edition><language>dan ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040719&DB=EPODOC&CC=DK&NR=175246B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040719&DB=EPODOC&CC=DK&NR=175246B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SASAKI, JUN</creatorcontrib><creatorcontrib>OGURA, HIROO</creatorcontrib><creatorcontrib>HIGURASHI, KUNIZOU</creatorcontrib><creatorcontrib>ARAKI, SHIN</creatorcontrib><creatorcontrib>TSUCHIYA, YUTAKA</creatorcontrib><creatorcontrib>KOZASA, MICHIKO</creatorcontrib><creatorcontrib>SUGIMOTO, HACHIRO</creatorcontrib><creatorcontrib>KARIBE, NORIE</creatorcontrib><creatorcontrib>IIMURA, YOICHI</creatorcontrib><creatorcontrib>KOZASA, TAKASHI</creatorcontrib><creatorcontrib>YAMATSU, KIYOMI</creatorcontrib><creatorcontrib>YAMANISHI, YOSHIHARU</creatorcontrib><creatorcontrib>KUBOTA, ATSUHIKO</creatorcontrib><title>New cyclic amine cpds</title><description>Cyclic amine cpds. of formula (I) and their salts are new. J is (a) a gp., opt. substd., of: phenyl, pyridyl, pyrazyl, cyclohexyl, quino(xa)lyl or furyl; (b) a monovalent or divalent gp., where the phenyl may have substit(s), of: indan(ol)yl, (iii) inden(on)yl, indan(edio)hyl, tetralonyl, benzosuberonyl, or C6H5-CO-CH(CH3)-; (c) a monovalent gp. derived from a cyclic amide cpd. (d) lower alkyl; or (e) R21-CH=CH- (R21 = H or (lower alkoxycarbonyl). B = (CHR22)r, CO(CHR22)r, NR4-(HCR22)r, CO-NR5-(CHR22)r, CH=CH-(CHR22)r, OCOO-(CHR22)r, OOC-NH-(CHR22)r, NH-CO-(CHR32)4, CH2CONH-(CHR22)r, (CH2)2CONH-(CHR22)r, CH(OH)-(CHR22)r, CH(OH)-(CHR22)r, = (CH-CH=CH)b, =CH-(CH2)c, =(CH-CH)d, COCH=CH-CH2, COCH2-CH(CH(OH)CH2, CH(CH3)CONHCH2, CH=CHCONH(CH2)2, NH, O, S, dialkylaminoalkylcarbonyl or lower alkoxycarbonyl; R4 = H, acyl, lower alkyl(sulphonyl), (substd.)phenyl, or (substd.)benzyl; R5 = H, lower alkyl or phenyl, r = 0-10; R22 = H or Me such that one alkylene may have no CH3 or one or more CH3; b = 1-3; c = 0-9; d = 0-5; T = N or C (i) Q = N, C or (i) q = 1-3; K = H, (substd.) phenyl, arylalkyl in which the phenyl may be substd. cinnamyl, lower alkyl, pyridylmethyl, cyclo(alkyl)alkyl, adamantanemethyl, furylmethyl, lower alkoxycarbonyl or acyl; and dotted lines is a single-or double-bond. 1-benzyl-4-((5,6-dimethoxy -1-indanon)- 2-ylidenyl)methyl) piperidine hydrochlorideis and example.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBD1Sy1XSK5MzslMVkjMzcxLVUguSCnmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxLt6G5qZGJmZOTobGRCgBAA6rIGU</recordid><startdate>20040719</startdate><enddate>20040719</enddate><creator>SASAKI, JUN</creator><creator>OGURA, HIROO</creator><creator>HIGURASHI, KUNIZOU</creator><creator>ARAKI, SHIN</creator><creator>TSUCHIYA, YUTAKA</creator><creator>KOZASA, MICHIKO</creator><creator>SUGIMOTO, HACHIRO</creator><creator>KARIBE, NORIE</creator><creator>IIMURA, YOICHI</creator><creator>KOZASA, TAKASHI</creator><creator>YAMATSU, KIYOMI</creator><creator>YAMANISHI, YOSHIHARU</creator><creator>KUBOTA, ATSUHIKO</creator><scope>EVB</scope></search><sort><creationdate>20040719</creationdate><title>New cyclic amine cpds</title><author>SASAKI, JUN ; OGURA, HIROO ; HIGURASHI, KUNIZOU ; ARAKI, SHIN ; TSUCHIYA, YUTAKA ; KOZASA, MICHIKO ; SUGIMOTO, HACHIRO ; KARIBE, NORIE ; IIMURA, YOICHI ; KOZASA, TAKASHI ; YAMATSU, KIYOMI ; YAMANISHI, YOSHIHARU ; KUBOTA, ATSUHIKO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DK175246BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>dan ; eng</language><creationdate>2004</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SASAKI, JUN</creatorcontrib><creatorcontrib>OGURA, HIROO</creatorcontrib><creatorcontrib>HIGURASHI, KUNIZOU</creatorcontrib><creatorcontrib>ARAKI, SHIN</creatorcontrib><creatorcontrib>TSUCHIYA, YUTAKA</creatorcontrib><creatorcontrib>KOZASA, MICHIKO</creatorcontrib><creatorcontrib>SUGIMOTO, HACHIRO</creatorcontrib><creatorcontrib>KARIBE, NORIE</creatorcontrib><creatorcontrib>IIMURA, YOICHI</creatorcontrib><creatorcontrib>KOZASA, TAKASHI</creatorcontrib><creatorcontrib>YAMATSU, KIYOMI</creatorcontrib><creatorcontrib>YAMANISHI, YOSHIHARU</creatorcontrib><creatorcontrib>KUBOTA, ATSUHIKO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SASAKI, JUN</au><au>OGURA, HIROO</au><au>HIGURASHI, KUNIZOU</au><au>ARAKI, SHIN</au><au>TSUCHIYA, YUTAKA</au><au>KOZASA, MICHIKO</au><au>SUGIMOTO, HACHIRO</au><au>KARIBE, NORIE</au><au>IIMURA, YOICHI</au><au>KOZASA, TAKASHI</au><au>YAMATSU, KIYOMI</au><au>YAMANISHI, YOSHIHARU</au><au>KUBOTA, ATSUHIKO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>New cyclic amine cpds</title><date>2004-07-19</date><risdate>2004</risdate><abstract>Cyclic amine cpds. of formula (I) and their salts are new. J is (a) a gp., opt. substd., of: phenyl, pyridyl, pyrazyl, cyclohexyl, quino(xa)lyl or furyl; (b) a monovalent or divalent gp., where the phenyl may have substit(s), of: indan(ol)yl, (iii) inden(on)yl, indan(edio)hyl, tetralonyl, benzosuberonyl, or C6H5-CO-CH(CH3)-; (c) a monovalent gp. derived from a cyclic amide cpd. (d) lower alkyl; or (e) R21-CH=CH- (R21 = H or (lower alkoxycarbonyl). B = (CHR22)r, CO(CHR22)r, NR4-(HCR22)r, CO-NR5-(CHR22)r, CH=CH-(CHR22)r, OCOO-(CHR22)r, OOC-NH-(CHR22)r, NH-CO-(CHR32)4, CH2CONH-(CHR22)r, (CH2)2CONH-(CHR22)r, CH(OH)-(CHR22)r, CH(OH)-(CHR22)r, = (CH-CH=CH)b, =CH-(CH2)c, =(CH-CH)d, COCH=CH-CH2, COCH2-CH(CH(OH)CH2, CH(CH3)CONHCH2, CH=CHCONH(CH2)2, NH, O, S, dialkylaminoalkylcarbonyl or lower alkoxycarbonyl; R4 = H, acyl, lower alkyl(sulphonyl), (substd.)phenyl, or (substd.)benzyl; R5 = H, lower alkyl or phenyl, r = 0-10; R22 = H or Me such that one alkylene may have no CH3 or one or more CH3; b = 1-3; c = 0-9; d = 0-5; T = N or C (i) Q = N, C or (i) q = 1-3; K = H, (substd.) phenyl, arylalkyl in which the phenyl may be substd. cinnamyl, lower alkyl, pyridylmethyl, cyclo(alkyl)alkyl, adamantanemethyl, furylmethyl, lower alkoxycarbonyl or acyl; and dotted lines is a single-or double-bond. 1-benzyl-4-((5,6-dimethoxy -1-indanon)- 2-ylidenyl)methyl) piperidine hydrochlorideis and example.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | New cyclic amine cpds |
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