Acylaminothiazolderivater og anvendelse deraf som beta-amyloid-hæmmere
Compounds of formula (I) as defined herein: inhibit the formation of the -amyloid peptide ( -A4) and are, therefore, useful in the treatment of pathologies in which a -amyloid peptide ( -A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheime...
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| creator | BALTZER, SYLVIE PASCAL, MARC VAN DORSSELAER, VIVIANE |
| description | Compounds of formula (I) as defined herein: inhibit the formation of the -amyloid peptide ( -A4) and are, therefore, useful in the treatment of pathologies in which a -amyloid peptide ( -A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy, cerebrovascular disorders, frontotemporal dementias and Pick's disease, post-traumatic dementias, pathologies linked to neuroinflammatory processes, Huntington's disease and Korsakov's syndrome. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Acylaminothiazolderivater og anvendelse deraf som beta-amyloid-hæmmere |
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