2,4,6-TRIIOD-ISOPHTHALSYREDERIVATER, FREMGANGSMAADE TIL FREMSTILLING DERAF OG ROENTGENKONTRASTMIDDEL INDEHOLDENDE DISSE FORBINDELSER

Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-( alpha -hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stab...

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Hauptverfasser: FELDER, ERNST, PITRE, DAVIDE
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description Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-( alpha -hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stability as well as resistance to hydrolysis. Methods for preparation and use of the compounds are also disclosed.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title 2,4,6-TRIIOD-ISOPHTHALSYREDERIVATER, FREMGANGSMAADE TIL FREMSTILLING DERAF OG ROENTGENKONTRASTMIDDEL INDEHOLDENDE DISSE FORBINDELSER
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