Analogy process for preparing polycyclic pyrazole compounds

Novel DNA constructs and expression products are provided related to the HIV virus, where the gp160 encoding sequence is mutated to prevent cleavage to the mature protein product. The mutated protein and the virion containing the mutated protein may serve as vaccines to protect a host against infect...

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1. Verfasser: MCCUNE, JOSEPH MCCRARY
Format: Patent
Sprache:dan ; eng
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Zusammenfassung:Novel DNA constructs and expression products are provided related to the HIV virus, where the gp160 encoding sequence is mutated to prevent cleavage to the mature protein product. The mutated protein and the virion containing the mutated protein may serve as vaccines to protect a host against infection and in the study of the maturation of gp160 and methods and compositions for inhibiting the maturation.