Aripiprazol-lægemiddelsubstans med lav hygroskopi og fremgangsmåde til fremstilling af denne
The present invention provides an improved low hygroscopic form, form E, of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an e...
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| creator | YABUUCHI, TSUYOSHI YAMADA, SHOHEI FUJIMOTO, KIYOSHI NISHIOKA, YOSHIHIRO TAKAHASHI, MASANORI OI, YOSHIHIRO SHINHAMA, KOICHI BANDO, TAKUJI AOKI, SATOSHI KAWASAKI, JUNICHI KOBAYASHI, NORIYUKI ISHIGAMI, MAKOTO NAKAGAWA, TOMONORI TOMINAGA, MICHIAKI TOMIKAWA, KENJI TANIGUCHI, YOUICHI FUJIMURA, TSUTOMU ABE, KAORU UTSUMI, NAOTO |
| description | The present invention provides an improved low hygroscopic form, form E, of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an extended period. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATION SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TRANSPORTING |
| title | Aripiprazol-lægemiddelsubstans med lav hygroskopi og fremgangsmåde til fremstilling af denne |
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