Thienodibenzoazulenforbindelser som tumornekrosefaktorhæmmere

The present invention relates to the dibenzoazulene compounds represented by formula I as well as to their pharmaceutical preparations for the inhibition of tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1) in mammals at all diseases and conditions where these mediators are excessive...

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Hauptverfasser: PESIC, DIJANA, MERCEP, MLADEN, HRVACIC, BOSKA, MESIC, MILAN, ZUPANOVIC, ZELJKO
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creator PESIC, DIJANA
MERCEP, MLADEN
HRVACIC, BOSKA
MESIC, MILAN
ZUPANOVIC, ZELJKO
description The present invention relates to the dibenzoazulene compounds represented by formula I as well as to their pharmaceutical preparations for the inhibition of tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1) in mammals at all diseases and conditions where these mediators are excessively secreted. The compounds of the present invention also demonstrate an analgetic action and can be used to relieve pain.
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subjects APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Thienodibenzoazulenforbindelser som tumornekrosefaktorhæmmere
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