Antiviralt virksom farmaceutisk olie-i-vandemulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf

An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water mis...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GEBHARD-HANSEN, KNUD ERIK, PEDERSEN, SOEREN BOLS, ALHEDE, BOERGE INGVAR FRISCH, LISSAU, BODIL GYLLEMBOURG, BJOERNSDOTTIR, KAREN
Format: Patent
Sprache:dan
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator GEBHARD-HANSEN, KNUD ERIK
PEDERSEN, SOEREN BOLS
ALHEDE, BOERGE INGVAR FRISCH
LISSAU, BODIL GYLLEMBOURG
BJOERNSDOTTIR, KAREN
description An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_DK111392A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>DK111392A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_DK111392A3</originalsourceid><addsrcrecordid>eNqFjj0LwjAQhrs4iPoX5MZ2yNB2cix-ILi6iZTQXm3oJSlJWszP8B97QneXe54XXu5unXwqE9SsnKQAjMFbDZ10WjY4BeUHsKRQKDFL06KeyCtrQLH3llpkwkE80kL0sXX2HTH0PDPNjPR8TdIoA6lsYkOW12eAROgAA_jfxSUZQB9YWnSy2yarTpLH3cJNsr-c78erwNHW6Ef-zGCoT7c8z8tDUZV_C1-GpU7B</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Antiviralt virksom farmaceutisk olie-i-vandemulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf</title><source>esp@cenet</source><creator>GEBHARD-HANSEN, KNUD ERIK ; PEDERSEN, SOEREN BOLS ; ALHEDE, BOERGE INGVAR FRISCH ; LISSAU, BODIL GYLLEMBOURG ; BJOERNSDOTTIR, KAREN</creator><creatorcontrib>GEBHARD-HANSEN, KNUD ERIK ; PEDERSEN, SOEREN BOLS ; ALHEDE, BOERGE INGVAR FRISCH ; LISSAU, BODIL GYLLEMBOURG ; BJOERNSDOTTIR, KAREN</creatorcontrib><description>An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.</description><edition>5</edition><language>dan</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1994</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19940310&amp;DB=EPODOC&amp;CC=DK&amp;NR=111392A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19940310&amp;DB=EPODOC&amp;CC=DK&amp;NR=111392A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GEBHARD-HANSEN, KNUD ERIK</creatorcontrib><creatorcontrib>PEDERSEN, SOEREN BOLS</creatorcontrib><creatorcontrib>ALHEDE, BOERGE INGVAR FRISCH</creatorcontrib><creatorcontrib>LISSAU, BODIL GYLLEMBOURG</creatorcontrib><creatorcontrib>BJOERNSDOTTIR, KAREN</creatorcontrib><title>Antiviralt virksom farmaceutisk olie-i-vandemulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf</title><description>An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1994</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjj0LwjAQhrs4iPoX5MZ2yNB2cix-ILi6iZTQXm3oJSlJWszP8B97QneXe54XXu5unXwqE9SsnKQAjMFbDZ10WjY4BeUHsKRQKDFL06KeyCtrQLH3llpkwkE80kL0sXX2HTH0PDPNjPR8TdIoA6lsYkOW12eAROgAA_jfxSUZQB9YWnSy2yarTpLH3cJNsr-c78erwNHW6Ef-zGCoT7c8z8tDUZV_C1-GpU7B</recordid><startdate>19940310</startdate><enddate>19940310</enddate><creator>GEBHARD-HANSEN, KNUD ERIK</creator><creator>PEDERSEN, SOEREN BOLS</creator><creator>ALHEDE, BOERGE INGVAR FRISCH</creator><creator>LISSAU, BODIL GYLLEMBOURG</creator><creator>BJOERNSDOTTIR, KAREN</creator><scope>EVB</scope></search><sort><creationdate>19940310</creationdate><title>Antiviralt virksom farmaceutisk olie-i-vandemulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf</title><author>GEBHARD-HANSEN, KNUD ERIK ; PEDERSEN, SOEREN BOLS ; ALHEDE, BOERGE INGVAR FRISCH ; LISSAU, BODIL GYLLEMBOURG ; BJOERNSDOTTIR, KAREN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DK111392A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>dan</language><creationdate>1994</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>GEBHARD-HANSEN, KNUD ERIK</creatorcontrib><creatorcontrib>PEDERSEN, SOEREN BOLS</creatorcontrib><creatorcontrib>ALHEDE, BOERGE INGVAR FRISCH</creatorcontrib><creatorcontrib>LISSAU, BODIL GYLLEMBOURG</creatorcontrib><creatorcontrib>BJOERNSDOTTIR, KAREN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GEBHARD-HANSEN, KNUD ERIK</au><au>PEDERSEN, SOEREN BOLS</au><au>ALHEDE, BOERGE INGVAR FRISCH</au><au>LISSAU, BODIL GYLLEMBOURG</au><au>BJOERNSDOTTIR, KAREN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Antiviralt virksom farmaceutisk olie-i-vandemulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf</title><date>1994-03-10</date><risdate>1994</risdate><abstract>An antivirally active pharmaceutical oil-in-water emulsion containing 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) or a salt or ester thereof as an active ingredient in the continuous aqueous phase, said phase in addition to said active ingredient and the dispersed oil phase containing a water miscible organic solvent, wherein a polyhydric alcohol may form a constituent. The emulsion comprises from 1 % to 10 % w/w of acyclovir or a salt or ester thereof, from 20 % to 50 % w/w of organic solvent comprising from 5 % to 50 % w/w glycerol formal and from 0 % to 29 % w/w of a polyhydric alcohol, and from 20 % to 40 % w/w water, said percentages being based on the total weight of the formulation. As a polyhydric alcohol propylene glycol may be used, and the emulsion may be available as a cream, wherein the oil phase comprises white vaseline, liquid paraffin (paraffin oil), glycerol monostearate, and stearic acid.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language dan
recordid cdi_epo_espacenet_DK111392A
source esp@cenet
subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Antiviralt virksom farmaceutisk olie-i-vandemulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T07%3A56%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GEBHARD-HANSEN,%20KNUD%20ERIK&rft.date=1994-03-10&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EDK111392A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true