Fremgangsmåde til forhindring af forkalkning af aldehyd-fikserede bioprotesematerialer

A method for preparing collagenous biological tissues for use as implantable bioprosthetic material, and articles prepared thereby. The method generally comprises the steps of a) contacting the tissue with an aldehyde fixative to effect cross-linking of the connective tissue protein(s) and subsequen...

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Hauptverfasser: DINH, TAN, THANH, LEE, CATHERINE, TING, PFADENHAUER, ERNEST, H, YANG, JUN
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creator DINH, TAN, THANH
LEE, CATHERINE, TING
PFADENHAUER, ERNEST, H
YANG, JUN
description A method for preparing collagenous biological tissues for use as implantable bioprosthetic material, and articles prepared thereby. The method generally comprises the steps of a) contacting the tissue with an aldehyde fixative to effect cross-linking of the connective tissue protein(s) and subsequently b) contacting the tissue with a polyglycidyl ether. The treatment of the crosslinked tissue with the polyglycidyl ether serves to mitigate the tissue's propensity to undergo calcification following implantation in the body.
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subjects BANDAGES, DRESSINGS OR ABSORBENT PADS
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PROSTHESES
TREATMENT OR PROTECTION OF EYES OR EARS
title Fremgangsmåde til forhindring af forkalkning af aldehyd-fikserede bioprotesematerialer
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