Phthalazinoner

PCT No. PCT/EP98/00124 Sec. 371 Date Jul. 14, 1999 Sec. 102(e) Date Jul. 14, 1999 PCT Filed Jan. 12, 1998 PCT Pub. No. WO98/31674 PCT Pub. Date Jul. 23, 1998Compounds of formula I wherein R1, R2, R3, R4 and R5 have the means set forth in the description are selective cyclic nucleotide phosphodiester...

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Hauptverfasser: HATZELMANN, ARMIN, BEUME, ROLF, VAN DER LAAN, IVONNE, JOHANNA, VAN DER MEY, MARGARETHA, HAEFNER, DIETRICH, BOSS, HILDEGARD, TIMMERMAN, HENDRIK, STERK, GEERT, JAN, KLEY, HANS-PETER
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creator HATZELMANN, ARMIN
BEUME, ROLF
VAN DER LAAN, IVONNE, JOHANNA
VAN DER MEY, MARGARETHA
HAEFNER, DIETRICH
BOSS, HILDEGARD
TIMMERMAN, HENDRIK
STERK, GEERT, JAN
KLEY, HANS-PETER
description PCT No. PCT/EP98/00124 Sec. 371 Date Jul. 14, 1999 Sec. 102(e) Date Jul. 14, 1999 PCT Filed Jan. 12, 1998 PCT Pub. No. WO98/31674 PCT Pub. Date Jul. 23, 1998Compounds of formula I wherein R1, R2, R3, R4 and R5 have the means set forth in the description are selective cyclic nucleotide phosphodiesterase (PDE) inhibitors (specifically of type 4), which are effective bronchial therapeutics.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Phthalazinoner
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