Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner

Improved process of compound of formula IIIin whichA denotes CH=CH or SW denotes OX denotes S, O or NR2 in which the residue R2 is hydrogen or C1-C6 alkyl,Y denotes CH or NR denotes naphthyl, thienyl or phenyl which is optionally monosubstituted or disubstituted with C1-C3 alkyl, CF3, C1-C3 alkoxy,...

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Hauptverfasser: KUEHNLE, HANS-FRIEDER, WITTE, ERNSTRISTIAN, WOLFF, HANS-PETER
Format: Patent
Sprache:dan
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Zusammenfassung:Improved process of compound of formula IIIin whichA denotes CH=CH or SW denotes OX denotes S, O or NR2 in which the residue R2 is hydrogen or C1-C6 alkyl,Y denotes CH or NR denotes naphthyl, thienyl or phenyl which is optionally monosubstituted or disubstituted with C1-C3 alkyl, CF3, C1-C3 alkoxy, F, Cl or bromine,R1 denotes hydrogen or C1-C6 alkyl andn denotes 1-3by reducing a compound of the general formula IV,in which A, W, X, Y, R, R1 and n have the meanings stated abovewith activated aluminium in a protic solvent,as well as new compounds of formula III and pharmaceutical preparations containing these compounds.