Fremstilling af hydroxyforbindelser ved bioomdannelse med dioxygenase

PCT No. PCT/GB96/01208 Sec. 371 Date Nov. 21, 1997 Sec. 102(e) Date Nov. 21, 1997 PCT Filed May 20, 1996 PCT Pub. No. WO96/37628 PCT Pub. Date Nov. 28, 1996A process for preparing a compound of Formula (3) in which R2 is -H; which comprises the steps: i) conversion of a compound of Formula (1) into...

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Hauptverfasser: DALTON, HOWARD, BOWERS, NIGEL, BLACKER, ANDREW, JOHN, BOYD, DEREK, RAYMOND
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Sprache:dan
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Zusammenfassung:PCT No. PCT/GB96/01208 Sec. 371 Date Nov. 21, 1997 Sec. 102(e) Date Nov. 21, 1997 PCT Filed May 20, 1996 PCT Pub. No. WO96/37628 PCT Pub. Date Nov. 28, 1996A process for preparing a compound of Formula (3) in which R2 is -H; which comprises the steps: i) conversion of a compound of Formula (1) into a compound of Formula (2) using a dioxygenase enzyme; ii) conversion of the compound of Formula (2) into a compound of Formula (3) wherein is -COR; and iii) conversion of the compound of Formula (3) in which R2 is -COR into a compound of Formula (3) in which R2 is -H; wherein R2, a, b, c, d, Z, m and X are as defined in claim 1. Also claimed are individual steps of the process and new compounds of Formula (2).