WACHSTUMSHORMON-FREISETZENDE OXINDOLDERIVATE

An oxindole of Formula 1 or a prodrug thereof, or a pharmaceutically acceptable salt thereof is useful for growth hormone releaser:whereinR1, R2, R3 and R4 are independently hydrogen, optionally substituted alkyl etc;R5 is optionally substituted aryl or optionally substituted heteroaryl;Z is -O- or...

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Hauptverfasser: TOKUNAGA, TERUHISA, UEKI, YASUYUKI, KUMAGAI, KAZUO, UMEZOME, TAKASHI, NAGATA, RYU, OKAZAKI, KAZUHIKO, HUME, EWAN
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creator TOKUNAGA, TERUHISA
UEKI, YASUYUKI
KUMAGAI, KAZUO
UMEZOME, TAKASHI
NAGATA, RYU
OKAZAKI, KAZUHIKO
HUME, EWAN
description An oxindole of Formula 1 or a prodrug thereof, or a pharmaceutically acceptable salt thereof is useful for growth hormone releaser:whereinR1, R2, R3 and R4 are independently hydrogen, optionally substituted alkyl etc;R5 is optionally substituted aryl or optionally substituted heteroaryl;Z is -O- or -NH-;one of W1 and W2 is hydrogen, alkyl or -Y-CON(R10)R11;the other of W1 and W2 isn is 1, 2 or 3; m is 0, 1, 2 or 3;Y is single bond or C1-C3 alkylene;R6 and R7 are independently hydrogen, optionally substituted alkyl etc;R8 and R9 are independently hydrogen, optionally substituted alkyl etc;R10 and R11 are independently hydrogen, alkyl etc.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title WACHSTUMSHORMON-FREISETZENDE OXINDOLDERIVATE
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