Chinoline und Chinazoline Verbindungen und ihre therapeutische Anwendung
Compounds of formula I, wherein R represents C1-4 alkoxy optionally substituted by one or more fluorine atoms, R represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2NH2; R represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroat...
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creator | COLLIS, ALAN JOHN FOX, DAVID NATHAN ABRAHAM |
description | Compounds of formula I, wherein R represents C1-4 alkoxy optionally substituted by one or more fluorine atoms, R represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2NH2; R represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring system as a whole being optionally substituted, X represents CH or N; and L is absent, or represents a cyclic group of formula Ia, or represents a chain of formula Ib, and pharmaceutically acceptable salts thereof, are useful in the treatment of a variety of disorders including benign prostatic hyperplasia. |
format | Patent |
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R represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring system as a whole being optionally substituted, X represents CH or N; and L is absent, or represents a cyclic group of formula Ia, or represents a chain of formula Ib, and pharmaceutically acceptable salts thereof, are useful in the treatment of a variety of disorders including benign prostatic hyperplasia.</description><edition>7</edition><language>ger</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030828&DB=EPODOC&CC=DE&NR=69811556T2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030828&DB=EPODOC&CC=DE&NR=69811556T2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>COLLIS, ALAN JOHN</creatorcontrib><creatorcontrib>FOX, DAVID NATHAN ABRAHAM</creatorcontrib><title>Chinoline und Chinazoline Verbindungen und ihre therapeutische Anwendung</title><description>Compounds of formula I, wherein R represents C1-4 alkoxy optionally substituted by one or more fluorine atoms, R represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2NH2; R represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring system as a whole being optionally substituted, X represents CH or N; and L is absent, or represents a cyclic group of formula Ia, or represents a chain of formula Ib, and pharmaceutically acceptable salts thereof, are useful in the treatment of a variety of disorders including benign prostatic hyperplasia.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPBwzsjMy8_JzEtVKM1LUQDxEqsg_LDUoqTMvJTSvPTUPLBkZkZRqkJJRmpRYkFqaUlmcXJGqoJjXnkqWA0PA2taYk5xKi-U5mZQcnMNcfbQTS3Ij08tLkhMTs1LLYl3cTWztDA0NDU1CwkxMiZKEQBFmDWU</recordid><startdate>20030828</startdate><enddate>20030828</enddate><creator>COLLIS, ALAN JOHN</creator><creator>FOX, DAVID NATHAN ABRAHAM</creator><scope>EVB</scope></search><sort><creationdate>20030828</creationdate><title>Chinoline und Chinazoline Verbindungen und ihre therapeutische Anwendung</title><author>COLLIS, ALAN JOHN ; FOX, DAVID NATHAN ABRAHAM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DE69811556TT23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>2003</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>COLLIS, ALAN JOHN</creatorcontrib><creatorcontrib>FOX, DAVID NATHAN ABRAHAM</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>COLLIS, ALAN JOHN</au><au>FOX, DAVID NATHAN ABRAHAM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Chinoline und Chinazoline Verbindungen und ihre therapeutische Anwendung</title><date>2003-08-28</date><risdate>2003</risdate><abstract>Compounds of formula I, wherein R represents C1-4 alkoxy optionally substituted by one or more fluorine atoms, R represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2NH2; R represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring system as a whole being optionally substituted, X represents CH or N; and L is absent, or represents a cyclic group of formula Ia, or represents a chain of formula Ib, and pharmaceutically acceptable salts thereof, are useful in the treatment of a variety of disorders including benign prostatic hyperplasia.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Chinoline und Chinazoline Verbindungen und ihre therapeutische Anwendung |
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