Chinoline und Chinazoline Verbindungen und ihre therapeutische Anwendung

Compounds of formula I, wherein R represents C1-4 alkoxy optionally substituted by one or more fluorine atoms, R represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2NH2; R represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroat...

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Hauptverfasser: COLLIS, ALAN JOHN, FOX, DAVID NATHAN ABRAHAM
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creator COLLIS, ALAN JOHN
FOX, DAVID NATHAN ABRAHAM
description Compounds of formula I, wherein R represents C1-4 alkoxy optionally substituted by one or more fluorine atoms, R represents an aryl group or a heteroaryl group, optionally substituted by C1-4 alkyl or SO2NH2; R represents a 4-, 5-, 6-, or 7-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N, O and S, the ring system as a whole being optionally substituted, X represents CH or N; and L is absent, or represents a cyclic group of formula Ia, or represents a chain of formula Ib, and pharmaceutically acceptable salts thereof, are useful in the treatment of a variety of disorders including benign prostatic hyperplasia.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Chinoline und Chinazoline Verbindungen und ihre therapeutische Anwendung
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