LACTON DERIVATE VON 17.BETA.-CARBOXY, CARBOTHIO UND AMIDE ANDROSTANVERBINDUNGEN

LACTON DERIVATE VON 17.BETA.-CARBOXY, CARBOTHIO UND AMIDE ANDROSTANVERBINDUNGEN

Compounds of the androstane series are described having general formulaand solvates thereof, in which R1 represents O, S or NH; R2 individually represents OC(=O)C1-6 alkyl; R3 individually represents hydrogen, methyl (which may be in either the alpha or beta configuration) or methylene; or R2 and R3...

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Hauptverfasser: BIGGADIKE, KEITH-GLAXO WELLCOME PLC, PROCOPIOU, ALEXANDROU-GLAXO WELLCOME
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CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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creator BIGGADIKE, KEITH-GLAXO WELLCOME PLC
PROCOPIOU, ALEXANDROU-GLAXO WELLCOME
description Compounds of the androstane series are described having general formulaand solvates thereof, in which R1 represents O, S or NH; R2 individually represents OC(=O)C1-6 alkyl; R3 individually represents hydrogen, methyl (which may be in either the alpha or beta configuration) or methylene; or R2 and R3 together representwhere R6 and R7 are the same or different and each represents hydrogen or C1-6 alkyl; R4 and R5 are the same or different and each represents hydrogen or halogen and represents a single or a double bond. These compounds and their solvates have use in medicine as anti-inflammatory or anti-allergic agents.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
title LACTON DERIVATE VON 17.BETA.-CARBOXY, CARBOTHIO UND AMIDE ANDROSTANVERBINDUNGEN
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