HUMANISIERTE MONOKLONALE ANTIKÖRPER GEGEN HUMANES INTERLEUKIN - 4

Humanized monoclonal antibodies are provided which are specific for human IL-4 and have properties unexpectedly superior to other, previously available humanized antibodies. Also provided are nucleic acids which encode the heavy and light chain variable regions of such monoclonal antibodies or antig...

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Hauptverfasser: TINDALL, STEPHEN, MADISON, NJ 07940, US, MURGOLO, NICHOLAS, MILLINGTON, NJ 07946, US, DALIE, BARBARA, BERKELEY HEIGHTS, NJ 07922, US, MILLER, KENNETH, CRANFORD, NJ 07016, US
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creator TINDALL, STEPHEN, MADISON, NJ 07940, US
MURGOLO, NICHOLAS, MILLINGTON, NJ 07946, US
DALIE, BARBARA, BERKELEY HEIGHTS, NJ 07922, US
MILLER, KENNETH, CRANFORD, NJ 07016, US
description Humanized monoclonal antibodies are provided which are specific for human IL-4 and have properties unexpectedly superior to other, previously available humanized antibodies. Also provided are nucleic acids which encode the heavy and light chain variable regions of such monoclonal antibodies or antigenic fragments thereof; anti-idiotypic antibodies; and methods for detecting, measuring and immunopurifying human IL-4, and for blocking or mimicking the biological activity of human IL-4.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title HUMANISIERTE MONOKLONALE ANTIKÖRPER GEGEN HUMANES INTERLEUKIN - 4
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