Cyclohexanderivate als Kaliumkanalaktivatoren

To provide a novel cyclohexane derivative, a cyclohexane derivative is defined by the formula (I) or a pharmacologically acceptable salt thereof: (wherein R and R may be the same or different from each other and each represents hydrogen or lower alkyl; R represents optionally substituted aryl or opt...

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Hauptverfasser: OINUMA, HITOSHI, IBARAKI, JP, ISHIBASHI, KEIJI, TSUKUBA-SHI, IBARAKI, JP, KABASAWA, YASUHIRO, TSUKUBA-SHI, IBARAKI, JP, SOUDA, SHIGERU, USHIKU-SHI, IBARAKI, JP, SHIRATO, MANABU, TSUKUBA-SHI, IBARAKI, JP, OGAWA, TOSHIAKI, NERIMA-KU, TOKYO, JP, MORIYA, KATSUHIRO, TSUKUBA-SHI, IBARAKI, JP, OZAKI, FUMIHIRO, USHIKU-SHI, IBARAKI, JP, HASEGAWA, TAKASHI, TSUKUBA-SHI, IBARAKI, JP, KATAYAMA, SATOSHI, TSUKUBA-SHI, IBARAKI, JP
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creator OINUMA, HITOSHI, IBARAKI, JP
ISHIBASHI, KEIJI, TSUKUBA-SHI, IBARAKI, JP
KABASAWA, YASUHIRO, TSUKUBA-SHI, IBARAKI, JP
SOUDA, SHIGERU, USHIKU-SHI, IBARAKI, JP
SHIRATO, MANABU, TSUKUBA-SHI, IBARAKI, JP
OGAWA, TOSHIAKI, NERIMA-KU, TOKYO, JP
MORIYA, KATSUHIRO, TSUKUBA-SHI, IBARAKI, JP
OZAKI, FUMIHIRO, USHIKU-SHI, IBARAKI, JP
HASEGAWA, TAKASHI, TSUKUBA-SHI, IBARAKI, JP
KATAYAMA, SATOSHI, TSUKUBA-SHI, IBARAKI, JP
description To provide a novel cyclohexane derivative, a cyclohexane derivative is defined by the formula (I) or a pharmacologically acceptable salt thereof: (wherein R and R may be the same or different from each other and each represents hydrogen or lower alkyl; R represents optionally substituted aryl or optionally substituted heteroaryl; X represents oxygen or sulfur; and Y represents a group represented by the formula: or the like). The compound of the present invention is useful as a preventive and therapeutic agent for diseases against which a potassium channel opening action is efficacious.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Cyclohexanderivate als Kaliumkanalaktivatoren
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