ANTIPSYCHOTISCHE BENZIMIDAZOLDERIVATE

PCT No. PCT/GB94/00607 Sec. 371 Date Dec. 20, 1995 Sec. 102(e) Date Dec. 20, 1995 PCT Filed Mar. 23, 1994 PCT Pub. No. WO94/22839 PCT Pub. Date Oct. 13, 1994A class of benzimidazole derivatives, substituted at the 2-position by a substituted piperazinylmethyl or piperazinylethyl moiety, are antagoni...

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Hauptverfasser:	KULAGOWSKI, JANUSZ JOZEF, HARLOW, ESSEX CM20 2QR, GB, LEESON, PAUL DAVID, HARLOW, ESSEX CM20 2QR, GB
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Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	KULAGOWSKI, JANUSZ JOZEF, HARLOW, ESSEX CM20 2QR, GB LEESON, PAUL DAVID, HARLOW, ESSEX CM20 2QR, GB
description	PCT No. PCT/GB94/00607 Sec. 371 Date Dec. 20, 1995 Sec. 102(e) Date Dec. 20, 1995 PCT Filed Mar. 23, 1994 PCT Pub. No. WO94/22839 PCT Pub. Date Oct. 13, 1994A class of benzimidazole derivatives, substituted at the 2-position by a substituted piperazinylmethyl or piperazinylethyl moiety, are antagonists of dopamine receptor subtypes within the brain, having a selective affinity for the dopamine D4 receptor subtype over other dopamine receptor subtypes, and are accordingly of benefit in the treatment and/or prevention of psychotic disorders such as schizophrenia whilst manifesting fewer side-effects than those associated with classical neuroleptic drugs.
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No. WO94/22839 PCT Pub. Date Oct. 13, 1994A class of benzimidazole derivatives, substituted at the 2-position by a substituted piperazinylmethyl or piperazinylethyl moiety, are antagonists of dopamine receptor subtypes within the brain, having a selective affinity for the dopamine D4 receptor subtype over other dopamine receptor subtypes, and are accordingly of benefit in the treatment and/or prevention of psychotic disorders such as schizophrenia whilst manifesting fewer side-effects than those associated with classical neuroleptic drugs.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	ANTIPSYCHOTISCHE BENZIMIDAZOLDERIVATE
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