Lipophile Zusammensetzungen von Oligosaccharid-Antibiotikasalzen
Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a base, e.g., NMG, an amount of, e.g., hydroxypropyl-b-cyclodextrin, and optionally a pharmaceutically ac...
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| creator | MILLER, GEORGE H., MONTVILLE, NEW JERSEY 07045, US PATEL, MAHESH, VERONA, NEW JERSEY 07044, US KWON, HEEWON Y., EDISON, NEW JERSEY 08820, US MORTON, JAMES B., BELLEVILLE, NEW JERSEY 07109, US GULLO, VINCENT P., LIBERTY CORNER, NEW JERSEY 07938, US HARE, ROBERTA, GILETTE, NEW JERSEY 07933, US LOEBENBERG, DAVID, MONSEY, NEW YORK 10952, US |
| description | Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a base, e.g., NMG, an amount of, e.g., hydroxypropyl-b-cyclodextrin, and optionally a pharmaceutically acceptable non-ionic surfactant, e.g., Tween-80, pharmaceutical compositions containing such compositions of matter, methods of treating and preventing susceptible bacterial infections in animals especially human beings as well as a method of preventing adverse reaction syndrome while simultaneously delivering an antiinfective amount of a lipophilic oligosaccharide antibiotic such as that of Formula III to said animals as well as the use of the compositions of matter for the preparation of a medicament for such treating or preventing are disclosed. |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS |
| title | Lipophile Zusammensetzungen von Oligosaccharid-Antibiotikasalzen |
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