CYCLOSPORIN ENTHALTENDE ORALE PHARMAZEUTISCHE ZUSAMMENSETZUNG SOWIE VERFAHREN ZU DEREN HERSTELLUNG
The invention relates to a pharmaceutical composition for oral administration containing cyclosporin A and/or cyclosporin G as active ingredient, which possess advantageous absorption characteristics, and to a process for preparing this composition. The composition according to the invention compris...
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| creator | KUERTHY, MARIA, H-1139 BUDAPEST, HU JUSZTIN, ISTVANNE, H-4028 DEBRECEN, HU MORAVCSIK, IMRE, H-1095 BUDAPEST, HU KOVACS, ISTVAN, H-4028 DEBRECEN, HU ORBAN, ERNOE, H-1118 BUDAPEST, HU KOVACS, ANTALNE, H-4028 DEBRECEN, HU JASZLITS, LASZLO, H-1129 BUDAPEST, HU BALOGH, TIBOR, H-1138 BUDAPEST, HU JANCSO, SANDOR, H-4028 DEBRECEN, HU TOMORI, LASZLONE, H-1045 BUDAPEST, HU TAKACS, ERZSEBET, H-4023 DEBRECEN, HU KISS, TAMASNE, H-4026 DEBRECEN, HU |
| description | The invention relates to a pharmaceutical composition for oral administration containing cyclosporin A and/or cyclosporin G as active ingredient, which possess advantageous absorption characteristics, and to a process for preparing this composition. The composition according to the invention comprises 1 part by mass of one or more cyclosporin(s) dissolved in 4 to 50 parts by volume of propylene glycol, 0 to 25 parts by volume of ethanol and 0.0 to 5 parts by mass of a polyoxyethylene/polyoxypropylene block polymer in homogenized state. Based on examinations carried out at 100 DEG C., the stability of solutions prepared according to the invention does not differ from that of the commercially available Sandimmun oral solution. |
| format | Patent |
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The composition according to the invention comprises 1 part by mass of one or more cyclosporin(s) dissolved in 4 to 50 parts by volume of propylene glycol, 0 to 25 parts by volume of ethanol and 0.0 to 5 parts by mass of a polyoxyethylene/polyoxypropylene block polymer in homogenized state. Based on examinations carried out at 100 DEG C., the stability of solutions prepared according to the invention does not differ from that of the commercially available Sandimmun oral solution.</description><edition>6</edition><language>ger</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960418&DB=EPODOC&CC=DE&NR=69114476T2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960418&DB=EPODOC&CC=DE&NR=69114476T2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUERTHY, MARIA, H-1139 BUDAPEST, HU</creatorcontrib><creatorcontrib>JUSZTIN, ISTVANNE, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>MORAVCSIK, IMRE, H-1095 BUDAPEST, HU</creatorcontrib><creatorcontrib>KOVACS, ISTVAN, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>ORBAN, ERNOE, H-1118 BUDAPEST, HU</creatorcontrib><creatorcontrib>KOVACS, ANTALNE, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>JASZLITS, LASZLO, H-1129 BUDAPEST, HU</creatorcontrib><creatorcontrib>BALOGH, TIBOR, H-1138 BUDAPEST, HU</creatorcontrib><creatorcontrib>JANCSO, SANDOR, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>TOMORI, LASZLONE, H-1045 BUDAPEST, HU</creatorcontrib><creatorcontrib>TAKACS, ERZSEBET, H-4023 DEBRECEN, HU</creatorcontrib><creatorcontrib>KISS, TAMASNE, H-4026 DEBRECEN, HU</creatorcontrib><title>CYCLOSPORIN ENTHALTENDE ORALE PHARMAZEUTISCHE ZUSAMMENSETZUNG SOWIE VERFAHREN ZU DEREN HERSTELLUNG</title><description>The invention relates to a pharmaceutical composition for oral administration containing cyclosporin A and/or cyclosporin G as active ingredient, which possess advantageous absorption characteristics, and to a process for preparing this composition. 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Based on examinations carried out at 100 DEG C., the stability of solutions prepared according to the invention does not differ from that of the commercially available Sandimmun oral solution.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNirEKwjAYBrs4iPoOP-4O1VJxDOlXU0iTkvxVzFKqxEm0UN8fK_gATndwN0-u8iK19Y11lSEYVkIzTAGyTmhQo4SrRUDLlZcKFFov6hrGg0NrjuTtuQKd4EqhHMzUqcBXFJxnaD1Ny2R27x9jXP24SNYlWKpNHF5dHIf-Fp_x3RXID2maZfucebv7a_oA6Dw1zA</recordid><startdate>19960418</startdate><enddate>19960418</enddate><creator>KUERTHY, MARIA, H-1139 BUDAPEST, HU</creator><creator>JUSZTIN, ISTVANNE, H-4028 DEBRECEN, HU</creator><creator>MORAVCSIK, IMRE, H-1095 BUDAPEST, HU</creator><creator>KOVACS, ISTVAN, H-4028 DEBRECEN, HU</creator><creator>ORBAN, ERNOE, H-1118 BUDAPEST, HU</creator><creator>KOVACS, ANTALNE, H-4028 DEBRECEN, HU</creator><creator>JASZLITS, LASZLO, H-1129 BUDAPEST, HU</creator><creator>BALOGH, TIBOR, H-1138 BUDAPEST, HU</creator><creator>JANCSO, SANDOR, H-4028 DEBRECEN, HU</creator><creator>TOMORI, LASZLONE, H-1045 BUDAPEST, HU</creator><creator>TAKACS, ERZSEBET, H-4023 DEBRECEN, HU</creator><creator>KISS, TAMASNE, H-4026 DEBRECEN, HU</creator><scope>EVB</scope></search><sort><creationdate>19960418</creationdate><title>CYCLOSPORIN ENTHALTENDE ORALE PHARMAZEUTISCHE ZUSAMMENSETZUNG SOWIE VERFAHREN ZU DEREN HERSTELLUNG</title><author>KUERTHY, MARIA, H-1139 BUDAPEST, HU ; JUSZTIN, ISTVANNE, H-4028 DEBRECEN, HU ; MORAVCSIK, IMRE, H-1095 BUDAPEST, HU ; KOVACS, ISTVAN, H-4028 DEBRECEN, HU ; ORBAN, ERNOE, H-1118 BUDAPEST, HU ; KOVACS, ANTALNE, H-4028 DEBRECEN, HU ; JASZLITS, LASZLO, H-1129 BUDAPEST, HU ; BALOGH, TIBOR, H-1138 BUDAPEST, HU ; JANCSO, SANDOR, H-4028 DEBRECEN, HU ; TOMORI, LASZLONE, H-1045 BUDAPEST, HU ; TAKACS, ERZSEBET, H-4023 DEBRECEN, HU ; KISS, TAMASNE, H-4026 DEBRECEN, HU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DE69114476TT23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1996</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KUERTHY, MARIA, H-1139 BUDAPEST, HU</creatorcontrib><creatorcontrib>JUSZTIN, ISTVANNE, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>MORAVCSIK, IMRE, H-1095 BUDAPEST, HU</creatorcontrib><creatorcontrib>KOVACS, ISTVAN, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>ORBAN, ERNOE, H-1118 BUDAPEST, HU</creatorcontrib><creatorcontrib>KOVACS, ANTALNE, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>JASZLITS, LASZLO, H-1129 BUDAPEST, HU</creatorcontrib><creatorcontrib>BALOGH, TIBOR, H-1138 BUDAPEST, HU</creatorcontrib><creatorcontrib>JANCSO, SANDOR, H-4028 DEBRECEN, HU</creatorcontrib><creatorcontrib>TOMORI, LASZLONE, H-1045 BUDAPEST, HU</creatorcontrib><creatorcontrib>TAKACS, ERZSEBET, H-4023 DEBRECEN, HU</creatorcontrib><creatorcontrib>KISS, TAMASNE, H-4026 DEBRECEN, HU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUERTHY, MARIA, H-1139 BUDAPEST, HU</au><au>JUSZTIN, ISTVANNE, H-4028 DEBRECEN, HU</au><au>MORAVCSIK, IMRE, H-1095 BUDAPEST, HU</au><au>KOVACS, ISTVAN, H-4028 DEBRECEN, HU</au><au>ORBAN, ERNOE, H-1118 BUDAPEST, HU</au><au>KOVACS, ANTALNE, H-4028 DEBRECEN, HU</au><au>JASZLITS, LASZLO, H-1129 BUDAPEST, HU</au><au>BALOGH, TIBOR, H-1138 BUDAPEST, HU</au><au>JANCSO, SANDOR, H-4028 DEBRECEN, HU</au><au>TOMORI, LASZLONE, H-1045 BUDAPEST, HU</au><au>TAKACS, ERZSEBET, H-4023 DEBRECEN, HU</au><au>KISS, TAMASNE, H-4026 DEBRECEN, HU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CYCLOSPORIN ENTHALTENDE ORALE PHARMAZEUTISCHE ZUSAMMENSETZUNG SOWIE VERFAHREN ZU DEREN HERSTELLUNG</title><date>1996-04-18</date><risdate>1996</risdate><abstract>The invention relates to a pharmaceutical composition for oral administration containing cyclosporin A and/or cyclosporin G as active ingredient, which possess advantageous absorption characteristics, and to a process for preparing this composition. The composition according to the invention comprises 1 part by mass of one or more cyclosporin(s) dissolved in 4 to 50 parts by volume of propylene glycol, 0 to 25 parts by volume of ethanol and 0.0 to 5 parts by mass of a polyoxyethylene/polyoxypropylene block polymer in homogenized state. Based on examinations carried out at 100 DEG C., the stability of solutions prepared according to the invention does not differ from that of the commercially available Sandimmun oral solution.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CYCLOSPORIN ENTHALTENDE ORALE PHARMAZEUTISCHE ZUSAMMENSETZUNG SOWIE VERFAHREN ZU DEREN HERSTELLUNG |
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