ANTI-IDIOTYP ANTIKÖRPER INDUKTION EINES ANTITUMORENRESPONSES

Novel compositions and methods are described for stimulating a patient's immune system to tumor cells which bear a gp72 tumor-associated antigen and thereby eliciting a tumoricidal effect. Anti-idiotypic human monoclonal antibodies and idiotopic regions thereof to primary antibodies which bind...

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Hauptverfasser: AUSTIN, ERIC, BERTRAM, NOTTINGHAM NG9 1LQ, GB, BALDWIN, ROBERT, WILLIAM, NOTTINGHAM NG10 4AJ, GB, DURRANT, LINDA, GILLIAN, NOTTINGHAM NG14 7BN, GB, BYERS, VERA, S., SAN FRANCISCO, CA 94114, US
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creator AUSTIN, ERIC, BERTRAM, NOTTINGHAM NG9 1LQ, GB
BALDWIN, ROBERT, WILLIAM, NOTTINGHAM NG10 4AJ, GB
DURRANT, LINDA, GILLIAN, NOTTINGHAM NG14 7BN, GB
BYERS, VERA, S., SAN FRANCISCO, CA 94114, US
description Novel compositions and methods are described for stimulating a patient's immune system to tumor cells which bear a gp72 tumor-associated antigen and thereby eliciting a tumoricidal effect. Anti-idiotypic human monoclonal antibodies and idiotopic regions thereof to primary antibodies which bind selectively to an antigenic determinant of gp72 are provided to mediate the humoral and cellular components of the patient's immune system. The immunogenic agents find use both in vivo and in vitro.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title ANTI-IDIOTYP ANTIKÖRPER INDUKTION EINES ANTITUMORENRESPONSES
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