Piperidinoalkyl-Derivate von Carbonsäure-Amiden

The present invention relates to unsaturated carboxylic acid amide derivatives of the formula wherein ring A stands for an optionally substituted aromatic ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue or forms an optionally substituted carbocyclic ring with the...

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Hauptverfasser: NAGAOKA, AKINOBU, KAWANISHI HYOGO 666-01, JP, GOTO, GIICHI, TOYONO-GUN OSAKA 563-01, JP
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creator NAGAOKA, AKINOBU, KAWANISHI HYOGO 666-01, JP
GOTO, GIICHI, TOYONO-GUN OSAKA 563-01, JP
description The present invention relates to unsaturated carboxylic acid amide derivatives of the formula wherein ring A stands for an optionally substituted aromatic ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue or forms an optionally substituted carbocyclic ring with the adjacent group -CH=C- together with two carbon atoms constituting the ring A; R stands for a hydrogen atom, an optionally substituted hydrocarbon residue or an optionally substituted acyl group; R stands for an optionally substituted hydrocarbon residue; and n denotes an integer ranging from 2 to 6, and salts thereof, as well as the production thereof. The compounds of the present invention act on the central nervous system of mammals and has a strong anti-cholinesterase activity, which can be used for the prophylaxis and therapy of, for example, senile dementia, Alzheimer's diseases, Huntington's chorea, et., and are useful as medicines.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Piperidinoalkyl-Derivate von Carbonsäure-Amiden
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