Piperidinoalkyl-Derivate von Carbonsäure-Amiden

The present invention relates to unsaturated carboxylic acid amide derivatives of the formula wherein ring A stands for an optionally substituted aromatic ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue or forms an optionally substituted carbocyclic ring with the...

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Bibliographische Detailangaben
Hauptverfasser: NAGAOKA, AKINOBU, KAWANISHI HYOGO 666-01, JP, GOTO, GIICHI, TOYONO-GUN OSAKA 563-01, JP
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The present invention relates to unsaturated carboxylic acid amide derivatives of the formula wherein ring A stands for an optionally substituted aromatic ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue or forms an optionally substituted carbocyclic ring with the adjacent group -CH=C- together with two carbon atoms constituting the ring A; R stands for a hydrogen atom, an optionally substituted hydrocarbon residue or an optionally substituted acyl group; R stands for an optionally substituted hydrocarbon residue; and n denotes an integer ranging from 2 to 6, and salts thereof, as well as the production thereof. The compounds of the present invention act on the central nervous system of mammals and has a strong anti-cholinesterase activity, which can be used for the prophylaxis and therapy of, for example, senile dementia, Alzheimer's diseases, Huntington's chorea, et., and are useful as medicines.