VERFAHREN ZUR HERSTELLUNG VON LIPOSOMEN MIT VERBESSERTER STABILITÄT WÄHREND DES TROCKNENS

A composition and method are provided for the making of cholesterol containing phospholipid liposomes such that when dried and then reconstituted, the liposomes retain their structure and size distribution as well as substantially all of the material that was originally encapsulated, and they behave...

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Hauptverfasser: FUJII, GARY, TORRANCE, CA 90504, US, SCHMIDT, PAUL, GARDNER, SAN MARINO, CA 91108, US
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creator FUJII, GARY, TORRANCE, CA 90504, US
SCHMIDT, PAUL, GARDNER, SAN MARINO, CA 91108, US
description A composition and method are provided for the making of cholesterol containing phospholipid liposomes such that when dried and then reconstituted, the liposomes retain their structure and size distribution as well as substantially all of the material that was originally encapsulated, and they behave biologically in a normal fashion. The cryoprotective agents are used in the aqueous medium to hydrate the phospholipid(s) and are a combination of at least one sugar and at least one protein, polypeptide, and/or oligopeptide.
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subjects CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR RELEVANT APPARATUS
TRANSPORTING
title VERFAHREN ZUR HERSTELLUNG VON LIPOSOMEN MIT VERBESSERTER STABILITÄT WÄHREND DES TROCKNENS
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