CYCLOHEXYLPHENYL VASOPRESSIN AGONISTEN

The present invention provides compounds of the general formulas: wherein Y is NR or -(CH2)n; R is H or alkyl; "Z" represents optionally substituted phenyl or a 6-membered aromatic ring having one nitrogen atom; "W" represents a optionally substituted phenyl or 5-membered aromati...

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Hauptverfasser: DUSZA, JOHN PAUL, FAILLI, AMEDEO ARTURO, SHUMSKY, JAY SCOTT, MEMOLI, KEVIN ANTHONY, CAGGIANO, THOMAS JOSEPH
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creator DUSZA, JOHN PAUL
FAILLI, AMEDEO ARTURO
SHUMSKY, JAY SCOTT
MEMOLI, KEVIN ANTHONY
CAGGIANO, THOMAS JOSEPH
description The present invention provides compounds of the general formulas: wherein Y is NR or -(CH2)n; R is H or alkyl; "Z" represents optionally substituted phenyl or a 6-membered aromatic ring having one nitrogen atom; "W" represents a optionally substituted phenyl or 5-membered aromatic ring having one nitrogen atom; "X" represents an optionally substituted 5-membered aromatic ring having one sulfur atom; as well as methods and pharmaceutical compositions utilizing these compounds for the inducing temporary delay of urination or treatment of disorders remedied by vasopressin agonist activity, including diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CYCLOHEXYLPHENYL VASOPRESSIN AGONISTEN
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