Prepn. of succinyl-choline-halide(s) - by reacting succinic acid di:alkyl ester with excess di:methyl-amino ethanol using alkali-alcoholate or -amide as catalyst, and reacting prod. with methyl halide
The prepn. of succinylcholine halide derivs. of formula (I) comprises (a) reacting a succinic acid dialkyl ester of formula (II) with excess dimethylamino methanol, in the presence of alkali-alcoholates or -amides as the catalyst and continuously distilling off the alcohol produced in the reaction;...
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