MENSCHLICHE GAMMA, DELTA-T-ZELLEN-ANTIGEN-REZEPTOR-POLYPEPTIDE UND NUKLEINSÄUREN

The present invention provides purified polypeptides which comprise at least a portion of a delta T cell receptor polypeptide, a gamma T cell receptor polypeptide, a gamma , gamma T cell receptor complex or a gamma , delta T cell receptor complex. Substances capable of forming complexes with these p...

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Bibliographische Detailangaben
Hauptverfasser: BRENNER, MICHAEL, B., ASHLAND, MA 01721, US, IP, STEPHEN, H., SUDBURY, MA 01776, US, SEIDMAN, JONATHAN, MILTON, MA 02186, US, BAND, HAMID, BOSTON, MA 02215, US
Format: Patent
Sprache:ger
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Zusammenfassung:The present invention provides purified polypeptides which comprise at least a portion of a delta T cell receptor polypeptide, a gamma T cell receptor polypeptide, a gamma , gamma T cell receptor complex or a gamma , delta T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.