DERIVAT DES INTERLEUKIN-2, SEINE HERSTELLUNG UND VERWENDUNG

Proteins whose amino-acid sequence essentially corresponds to that of natural interleukin-2 (IL-2) but which lacks the first 7 N-terminal amino acids display the biological activity of IL-2. These proteins can be prepared by genetic manipulation. They are suitable for the preparation of pharmaceutic...

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Hauptverfasser: MERTZ,RONALD,DR, ENGELS,JOACHIM,DR, LEINEWEBER,MICHAEL,DR, MUELLNER,HUBERT,DR, UHLMAN,EUGEN,DR, WENGENMAYER,FRIEDRICH,DR, WINNACKER,ERNST-LUDWIG,DR
Format: Patent
Sprache:ger
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Zusammenfassung:Proteins whose amino-acid sequence essentially corresponds to that of natural interleukin-2 (IL-2) but which lacks the first 7 N-terminal amino acids display the biological activity of IL-2. These proteins can be prepared by genetic manipulation. They are suitable for the preparation of pharmaceuticals with IL-2 activity.