ANTHRACYCLIN-DERIVATE, EIN MIKROBIOLOGISCHES VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS CYTOSTATIKA

The present invention relates to the micro-organism Streptomyces purpurascens (DSM 2658), its mutants and variants, a process for the preparation of anthracycline derivatives by fermentation of these cultures and to the anthracycline derivatives themselves. The new compounds are distinguished by ant...

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Hauptverfasser: ARETZ, WERNER., 6233 KELKHEIM, DE, SEDLACEK, HANS-HARALD., 3550 MARBURG, DE, FEHLHABER, HANS-WOLFRAM., 6270 IDSTEIN, DE, KRAEMER, HANS PETER, GANDHI, JULIA., BANDRA, BOMBAY, IN, REDDY, GAUKNAPALLI CHANDRASEKHAR, MULUND, BOMBAY, IN, GANGULI, BIMAL NARESH., BURE, BOMBAY, IN, BERSCHEID, HANS GERD., 6231 SCHWALBACH, DE, HUBER, GERHARD., 6233 KELKHEIM, DE, SOOD, RATAN SAGAR., MANKHURD, BOMBAY, IN
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creator ARETZ, WERNER., 6233 KELKHEIM, DE
SEDLACEK, HANS-HARALD., 3550 MARBURG, DE
FEHLHABER, HANS-WOLFRAM., 6270 IDSTEIN, DE
KRAEMER, HANS PETER
GANDHI, JULIA., BANDRA, BOMBAY, IN
REDDY, GAUKNAPALLI CHANDRASEKHAR, MULUND, BOMBAY, IN
GANGULI, BIMAL NARESH., BURE, BOMBAY, IN
BERSCHEID, HANS GERD., 6231 SCHWALBACH, DE
HUBER, GERHARD., 6233 KELKHEIM, DE
SOOD, RATAN SAGAR., MANKHURD, BOMBAY, IN
description The present invention relates to the micro-organism Streptomyces purpurascens (DSM 2658), its mutants and variants, a process for the preparation of anthracycline derivatives by fermentation of these cultures and to the anthracycline derivatives themselves. The new compounds are distinguished by antibacterial activity and, in addition, they act against various types of tumors.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title ANTHRACYCLIN-DERIVATE, EIN MIKROBIOLOGISCHES VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS CYTOSTATIKA
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