ANTHRACYCLIN-DERIVATE, EIN MIKROBIOLOGISCHES VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS CYTOSTATIKA

The present invention relates to the micro-organism Streptomyces purpurascens (DSM 2658), its mutants and variants, a process for the preparation of anthracycline derivatives by fermentation of these cultures and to the anthracycline derivatives themselves. The new compounds are distinguished by ant...

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Hauptverfasser:	ARETZ, WERNER., 6233 KELKHEIM, DE, SEDLACEK, HANS-HARALD., 3550 MARBURG, DE, FEHLHABER, HANS-WOLFRAM., 6270 IDSTEIN, DE, KRAEMER, HANS PETER, GANDHI, JULIA., BANDRA, BOMBAY, IN, REDDY, GAUKNAPALLI CHANDRASEKHAR, MULUND, BOMBAY, IN, GANGULI, BIMAL NARESH., BURE, BOMBAY, IN, BERSCHEID, HANS GERD., 6231 SCHWALBACH, DE, HUBER, GERHARD., 6233 KELKHEIM, DE, SOOD, RATAN SAGAR., MANKHURD, BOMBAY, IN
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the micro-organism Streptomyces purpurascens (DSM 2658), its mutants and variants, a process for the preparation of anthracycline derivatives by fermentation of these cultures and to the anthracycline derivatives themselves. The new compounds are distinguished by antibacterial activity and, in addition, they act against various types of tumors.