NEUE 1-BENZYL-4-(4-(2-PYRIMIDINYLAMINO)-BENZYL)-2,3-DIOXOPIPERAZIN-DERIVATE, SALZE DERSELBEN, VERFAHREN ZUR HERSTELLUNG DERSELBEN UND CARCINOSTATISCHE MITTEL MIT EINEM GEHALT DERSELBEN

1-Benzyl-4-[4-(2-pyrimidinylamino)benzyl]- 2,3-dioxopiperazine derivatives represented by the formula: wherein R is optionally substituted hydrocarbyl or acyl, R is H or alkyl and X is O or S, and salts thereof have an excellent carcinostatic activity but a low toxicity. Therefore, said compounds ar...

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Hauptverfasser:	KISHIMOTO,SUMIKO, TSUDA,HISATSUGU, TAKENO,RYUKO, HORI,TAKAKO, KIBA,YASUO, NAKANO,JOJI, NITTA,JUN, MURAKAMI,SHOHACHI, SAIKAWA,ISAMU, YOSHIDA,CHOSAKU
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	1-Benzyl-4-[4-(2-pyrimidinylamino)benzyl]- 2,3-dioxopiperazine derivatives represented by the formula: wherein R is optionally substituted hydrocarbyl or acyl, R is H or alkyl and X is O or S, and salts thereof have an excellent carcinostatic activity but a low toxicity. Therefore, said compounds are useful as medicines and also as intermediates.