3-Amino-beta-lactam-1-sulfonsäuren und ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel

Beta lactams (I) having an SO3M substit. at 1-position and an opt. substd. or protected amino gp. or azido gp. at the 3-position are new. (M is hydrogen or a cation). They can also be substd. at the 4-position by alkyl, cycloalkyl, opt. substd. phenyl, alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-pheny...

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Hauptverfasser:	CIMARUSTI, CHRISTOPHER MICHAEL, PENNINGTON, N.J., US, FRITZ, ALAN WILLIAM, KENDALL PARK, N.J., US, SYKES, RICHARD BROOK, BELLE MEAD, N.J., US, KOSTER, WILLIAM HENRY, RINGOES, N.J., US, PARKER, WILLIAM LAWRENCE, PENNINGTON, N.J., US, SLUSARCHYK, WILLIAM ALLEN, BELLE MEAD, N.J., US, FLOYD, DAVID MACK, PENNINGTON, N.J., US
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Beta lactams (I) having an SO3M substit. at 1-position and an opt. substd. or protected amino gp. or azido gp. at the 3-position are new. (M is hydrogen or a cation). They can also be substd. at the 4-position by alkyl, cycloalkyl, opt. substd. phenyl, alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl or 2-phenylethynyl. (I) having a 3-acylamino substit. are antibacterials effective against Gram negative and positive species, and useful therapeutically in human or veterinary medicine. The other new cpds. are intermediates.