Analgesic use of tyrosine-O-sulphate poly:peptide cpds. - e.g. phyllo:caerulin and ceruletide in human and veterinary therapy
Use of tyrosine-O-sulphate polypeptides (I) as analgesics in human and veterinary therapy is new X-Tyr(SO3H)-Y-Gly-Trp-W-Asp-Phc-NH2 (I) (X is H, t-butoxycarbonyl (Boc), Asp, Pyr-Glu, Pyr-Gln-Asp or Pyr-Asn-Asp; Y is Thr, Met, Leu, Nle or Val; and W is Met, Nle or Leu). The polypeptides (I), which i...
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