VERFAHREN ZUR HERSTELLUNG VON 3-HYDROXY-6-PHENYL-1,2,3,4-TETRAHYDRO- 1,5-BENZODIAZOCINEN
1. Process for the production of 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazoci- nes of the general Formula I see diagramm : EP0004024,P13,F1 as well as their acid addition salts, in which R is a hydrogen atom or a methyl group, R1 is a phenyl-, 2-halophenyl or 2-trifluoromethyl-phenyl group...
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creator | ZEUGNER,HORST,.ER.NAT LIEPMANN,HANS,.ER.NAT MILKOWSKI,WOLFGANG,.ER.NAT HUESCHENS,ROLF,.ER.NAT |
description | 1. Process for the production of 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazoci- nes of the general Formula I see diagramm : EP0004024,P13,F1 as well as their acid addition salts, in which R is a hydrogen atom or a methyl group, R1 is a phenyl-, 2-halophenyl or 2-trifluoromethyl-phenyl group and R2 is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, characterized in that 2-aminobenzophenones of the general Formula II see diagramm : EP0004024,P13,F2 in which R, R1 and R2 have the meanings defined above, or their acid addition salts are cyclised at elevated temperature in the presence of an inert organic solvent. |
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Process for the production of 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazoci- nes of the general Formula I see diagramm : EP0004024,P13,F1 as well as their acid addition salts, in which R is a hydrogen atom or a methyl group, R1 is a phenyl-, 2-halophenyl or 2-trifluoromethyl-phenyl group and R2 is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, characterized in that 2-aminobenzophenones of the general Formula II see diagramm : EP0004024,P13,F2 in which R, R1 and R2 have the meanings defined above, or their acid addition salts are cyclised at elevated temperature in the presence of an inert organic solvent.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1979</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEKwjAUgOEsDqLeIQfIA9NU0TG2r6YQXiSmpelSisRJtFDvjyAewOkfvn_JuhZ9pY1H4n3juUF_DWhtQ2feOuIKTCy96yLs4WKQogUpMqFEDgGD118FLsUOTki9K2vdu6ImpDVb3MfHnDa_rhivMBQG0vQa0jyNt_RM76HE7CC3Kj9qqf5YPliaMDo</recordid><startdate>19790920</startdate><enddate>19790920</enddate><creator>ZEUGNER,HORST,.ER.NAT</creator><creator>LIEPMANN,HANS,.ER.NAT</creator><creator>MILKOWSKI,WOLFGANG,.ER.NAT</creator><creator>HUESCHENS,ROLF,.ER.NAT</creator><scope>EVB</scope></search><sort><creationdate>19790920</creationdate><title>VERFAHREN ZUR HERSTELLUNG VON 3-HYDROXY-6-PHENYL-1,2,3,4-TETRAHYDRO- 1,5-BENZODIAZOCINEN</title><author>ZEUGNER,HORST,.ER.NAT ; LIEPMANN,HANS,.ER.NAT ; MILKOWSKI,WOLFGANG,.ER.NAT ; HUESCHENS,ROLF,.ER.NAT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DE2810349A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1979</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZEUGNER,HORST,.ER.NAT</creatorcontrib><creatorcontrib>LIEPMANN,HANS,.ER.NAT</creatorcontrib><creatorcontrib>MILKOWSKI,WOLFGANG,.ER.NAT</creatorcontrib><creatorcontrib>HUESCHENS,ROLF,.ER.NAT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZEUGNER,HORST,.ER.NAT</au><au>LIEPMANN,HANS,.ER.NAT</au><au>MILKOWSKI,WOLFGANG,.ER.NAT</au><au>HUESCHENS,ROLF,.ER.NAT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>VERFAHREN ZUR HERSTELLUNG VON 3-HYDROXY-6-PHENYL-1,2,3,4-TETRAHYDRO- 1,5-BENZODIAZOCINEN</title><date>1979-09-20</date><risdate>1979</risdate><abstract>1. Process for the production of 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazoci- nes of the general Formula I see diagramm : EP0004024,P13,F1 as well as their acid addition salts, in which R is a hydrogen atom or a methyl group, R1 is a phenyl-, 2-halophenyl or 2-trifluoromethyl-phenyl group and R2 is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, characterized in that 2-aminobenzophenones of the general Formula II see diagramm : EP0004024,P13,F2 in which R, R1 and R2 have the meanings defined above, or their acid addition salts are cyclised at elevated temperature in the presence of an inert organic solvent.</abstract><edition>2</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | VERFAHREN ZUR HERSTELLUNG VON 3-HYDROXY-6-PHENYL-1,2,3,4-TETRAHYDRO- 1,5-BENZODIAZOCINEN |
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