SUBSTITUIERTE ALPHA-AMINOOXYCARBONSAEUREHYDRAZIDDERIVATE UND IHRE SAEUREADDITIONSSALZE SOWIE IHRE VERWENDUNG UND VERFAHREN ZUR HERSTELLUNG DERSELBEN

Substituted alpha -aminooxycarbohydrazide derivatives of the formula I are obtained by reacting an alpha -aminooxycarbohydrazide with a compound of the general formula X = O. The substituents have the following meaning: X is a cycloalkylidene radical or a methylene group which is substituted by an a...

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Hauptverfasser: KISFALUDY,LAJOS,DR, DANCSI,LAJOS, FEKETE,GYOERGY,DR, SZABO,ISTVAN,DR, LUKATS PATTHY GEB
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DANCSI,LAJOS
FEKETE,GYOERGY,DR
SZABO,ISTVAN,DR
LUKATS PATTHY GEB
description Substituted alpha -aminooxycarbohydrazide derivatives of the formula I are obtained by reacting an alpha -aminooxycarbohydrazide with a compound of the general formula X = O. The substituents have the following meaning: X is a cycloalkylidene radical or a methylene group which is substituted by an alkyl radical with 1-5 carbon atoms and/or phenyl or furyl radical which is optionally substituted by halogen, hydroxyl, nitro and/or amino groups; R is hydrogen or a benzyl radical Y is hydrogen Z is an acyl radical derived from a pyridinecarboxylic acid or Y and Z together are one of the substituents which X can represent. The compounds are valuable tuberculostatics. Compounds substituted on the hydrazide group by isonicotinoyl or 5-nitrofurfurylidene group are particularly effective.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SUBSTITUIERTE ALPHA-AMINOOXYCARBONSAEUREHYDRAZIDDERIVATE UND IHRE SAEUREADDITIONSSALZE SOWIE IHRE VERWENDUNG UND VERFAHREN ZUR HERSTELLUNG DERSELBEN
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