High yield prodn. of partly known 3-amino-1,2,4-thiadiazoles - by reacting acylguanidines, thiono esters and strong base, then cyclisation with bromine

3-Amino-1,2,4-thaidiazoles of formula (i): where R = H, opt. halogenated 1-18C alkyl, aralkyl or phenyl opt. substd. by halogen, NO2, CF3 or lower alkyl; are prepd. by reacting the acylguanidine where R1 = 1-18C alkanoyl or benzoyl opt. substd. by halogen, NO2, NH2, alkoxy, acetamido or lower alkyl,...

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Sprache:eng ; ger
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