Multivalente Antikörper-Konstrukte
The invention relates to a multivalent Fv antibody construct comprising at least four variable domains which are connected to one another via peptide linkers 1, 2 and 3. The invention also relates to expression plasmids which code for such an Fv antibody construct. In addition, the invention relates...
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| creator | LITTLE, MELVYN KIPRIYANOV, SERGEJ |
| description | The invention relates to a multivalent Fv antibody construct comprising at least four variable domains which are connected to one another via peptide linkers 1, 2 and 3. The invention also relates to expression plasmids which code for such an Fv antibody construct. In addition, the invention relates to a method for producing the Fv antibody constructs and to the use thereof.
Die vorliegende Erfindung betrifft ein multivalentes F¶v¶-Antikörper-Konstrukt mit mindestens vier variablen Domänen, die über die Peptidlinker 1, 2 und 3 miteinander verbunden sind. Ferner betrifft die Erfindung Expressionsplasmide, die für ein solches F¶v¶-Antikörper-Konstrukt codieren, und ein Verfahren zur Herstellung der F¶v¶-Antikörper-Konstrukte sowie deren Verwendung. |
| format | Patent |
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Die vorliegende Erfindung betrifft ein multivalentes F¶v¶-Antikörper-Konstrukt mit mindestens vier variablen Domänen, die über die Peptidlinker 1, 2 und 3 miteinander verbunden sind. Ferner betrifft die Erfindung Expressionsplasmide, die für ein solches F¶v¶-Antikörper-Konstrukt codieren, und ein Verfahren zur Herstellung der F¶v¶-Antikörper-Konstrukte sowie deren Verwendung.</description><edition>6</edition><language>ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19991111&DB=EPODOC&CC=DE&NR=19819846A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19991111&DB=EPODOC&CC=DE&NR=19819846A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LITTLE, MELVYN</creatorcontrib><creatorcontrib>KIPRIYANOV, SERGEJ</creatorcontrib><title>Multivalente Antikörper-Konstrukte</title><description>The invention relates to a multivalent Fv antibody construct comprising at least four variable domains which are connected to one another via peptide linkers 1, 2 and 3. The invention also relates to expression plasmids which code for such an Fv antibody construct. In addition, the invention relates to a method for producing the Fv antibody constructs and to the use thereof.
Die vorliegende Erfindung betrifft ein multivalentes F¶v¶-Antikörper-Konstrukt mit mindestens vier variablen Domänen, die über die Peptidlinker 1, 2 und 3 miteinander verbunden sind. Ferner betrifft die Erfindung Expressionsplasmide, die für ein solches F¶v¶-Antikörper-Konstrukt codieren, und ein Verfahren zur Herstellung der F¶v¶-Antikörper-Konstrukte sowie deren Verwendung.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1999</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD2Lc0pySxLzEnNK0lVcMwrycw-vK2oILVI1zs_r7ikqDS7JJWHgTUtMac4lRdKczMourmGOHvophbkx6cWFyQmp-allsS7uBpaWgCRiZmjoTExagBpuCfC</recordid><startdate>19991111</startdate><enddate>19991111</enddate><creator>LITTLE, MELVYN</creator><creator>KIPRIYANOV, SERGEJ</creator><scope>EVB</scope></search><sort><creationdate>19991111</creationdate><title>Multivalente Antikörper-Konstrukte</title><author>LITTLE, MELVYN ; KIPRIYANOV, SERGEJ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DE19819846A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ger</language><creationdate>1999</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>LITTLE, MELVYN</creatorcontrib><creatorcontrib>KIPRIYANOV, SERGEJ</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LITTLE, MELVYN</au><au>KIPRIYANOV, SERGEJ</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Multivalente Antikörper-Konstrukte</title><date>1999-11-11</date><risdate>1999</risdate><abstract>The invention relates to a multivalent Fv antibody construct comprising at least four variable domains which are connected to one another via peptide linkers 1, 2 and 3. The invention also relates to expression plasmids which code for such an Fv antibody construct. In addition, the invention relates to a method for producing the Fv antibody constructs and to the use thereof.
Die vorliegende Erfindung betrifft ein multivalentes F¶v¶-Antikörper-Konstrukt mit mindestens vier variablen Domänen, die über die Peptidlinker 1, 2 und 3 miteinander verbunden sind. Ferner betrifft die Erfindung Expressionsplasmide, die für ein solches F¶v¶-Antikörper-Konstrukt codieren, und ein Verfahren zur Herstellung der F¶v¶-Antikörper-Konstrukte sowie deren Verwendung.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
| title | Multivalente Antikörper-Konstrukte |
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